Biocidal effects of organotin compounds, such as antibacterial, antifungal, and antipestal activity, are well documented. A few organotin (IV) derivatives in 1:1 [BuSn(L)(OPri)] have been produced. The reaction between monobutyltin triisopropoxide and 1-Hydroxy-2-naphthoic acid produces 1:2 [BuSn(LH)2(OPri)], 1:3 [BuSn(LH)3], and 2:1 [(BuSn)2L(OPri)4] molar ratios (where L = 1-Hydroxy-2-naphthoic acid). Elemental studies, as well as IR and NMR experimental techniques, were used to investigate the produced derivatives. By knowing the Minimum Inhibitory Concentration (MIC) values on gramme positive (Staphylococcus aureus) and gramme negative (Escherichia coli) bacteria, as well as Aspergillus niger and Candida albicans fungi, the derivatives were evaluated for antibacterial and antifungal activity. Antipestal properties against the pest Tribolium castaneum were also tested on the compounds. These compounds outperformed the comparable ligand in terms of biocidal activity.
Author(S) Details
Pankaj Mittal
Department of Chemistry, Anand Engineering College, Keetham, Agra, 282 007, India.
Manoj Kumar Pachouri
Department of Chemistry, Anand Engineering College, Keetham, Agra, 282 007, India.
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