Sunday 13 June 2021

Kasabach-Merrit Syndrome with Congenital Hemangioma: A Case Report | Chapter 9 | Highlights on Medicine and Medical Research Vol. 12

 Haemangioma, a vascular disease produced by excessive blood vessel proliferation, is the most common paediatric neoplasm. Haemangiomas are congenital lesions that affect newborns, children, and infants. They're usually harmless and go away on their own. They can induce difficulties due to their size, involvement of important organs, and associated coagulopathy such Kasabach-Merritt syndrome in 3 to 5% of patients. Kasabach Meritt Syndrome (KMS) is a genetic disorder. An growing haemangioma, excessive thrombocytopenia, and consumption coagulopathy characterise this potentially lethal coagulopathy. In rare circumstances, KMS is linked to kaposiform hemangioendothelioma (KHE), tufted angiomas, and congenital haemangiomas (CHs). Nearly 200 cases have been described in the literature since Kasabach and Merritt identified the first case in 1940. More than 80% of instances occur during the first year of life. An early diagnosis and treatment regimen are linked to a better prognosis. The most effective first-line treatment is steroid therapy.

Author(s) Details

Dr. V. Archana
Department of Pediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamilnadu, India.

S. Sundari
Department of Pediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamilnadu, India.

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