COPD (chronic obstructive pulmonary disease) is a worldwide health issue. The goal of this study was to look at how COPD affects quality of life and biomarker levels in COPD patients using particular biomarkers. A total of 116 COPD patients were included in the study, who were treated at a tertiary care center in the eastern portion of India. The GOLD standard was used to determine the severity of their COPD. Quality of life and biomarker levels were determined using the SGRQ-C and suitable biochemical techniques, respectively. Serum nitrate decreased (33.67 4.41 mol/L) whereas serum MDA increased (6.38 2.32 nmol/L), indicating enhanced nitrosative and oxidative stress, respectively. Overall, researchers discovered that the severity of COPD had a proportional impact on quality of life. There is an increase in nitrosative stress in COPD patients, as evidenced by a decline in NOS (serum nitrate), and an increase in oxidative stress, as seen by a high amount of MDA in the blood. There is a link between the severity of COPD and serum NOS and MDA levels.
Author (s) DetailsDr. Arijit Nag
Department of General Medicine, Calcutta National Medical College and Hospital, Kolkata, India.
Dr. Soma Chakrabarti
Department of Community Medicine, Calcutta National Medical College, Kolkata, India.
Dr. Anindya Dasgupta
Department of Biochemistry, Calcutta National Medical College, Kolkata, India.
View Book :- https://stm.bookpi.org/HMMS-V1/article/view/1176
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