Microbial Immunology | Book Publisher International

The book “Microbial Immunology” is organised to fulfil an area of immunology that attracts many scholars whome have an interest in immunology of human microbial infectious diseases. Many books tackle the science of basic and medical immunology in comparison few were having this topic in a separate book title or separate monograph title. This book tried to stand as a textbook in this attractive field of immunology. The layout of the text was organised in two parts, six sections and 40 chapters. The first part was with three sections: the basic immunology in 13 chapters, basic infect-ology in five chapters and basic microbial immunology in five chapters. The second part covered applied immunology with three sections the first, the immunology of common infections in five chapters, the immunology of emerging and re-emerging infections in nine chapters and the themes in three chapters that covered the immunology of polymicrobial infections, infectious granuloma and infectious secondary cryoglobulinemia. The book was intended to be of use for undergraduate students, post-graduate students and researchers of basic and microbial immunology. As well as laboratory medicine professionals.

 

Author (s) Details

IBRAHIM M.S. SHNAWA
Department of Medical Biotechnology, College of Biotechnology, AL-Qasim Green University, Qasim, Babylon, Iraq and College of Nursing, University of Hilla Hilla, Babylon, Iraq.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49970-50-2

 

Navigating the Health Implications of Post-COVID-19 Vaccination: A Comprehensive Review | Chapter 5 | Disease and Health Research: New Insights Vol. 6

 

The review conducts a thorough analysis of the literature on post-vaccination health effects, combining lessons from past years' research evaluations with the most recent studies. This book chapter investigates the complex setting of post-COVID-19 vaccination health implications, integrating insights from a spectrum of research endeavors. It explores the multifaceted impacts on the immune system, encompassing discussions on cytokine storms, susceptibility variations among different populations, autoimmune manifestations, and the emergence of long-term effects such as chronic inflammation and the enigmatic long COVID-19 syndrome. Additionally, the chapter navigates through management strategies and potential therapeutic interventions, aiming to offer a roadmap for healthcare professionals and policymakers to comprehend and address the complex results of COVID-19 vaccination. This comprehensive review provides useful insights for navigating the post-COVID-19 vaccine health implications and an overview of the immune system.

 

Author (s) Details

Ketankumar R Jansari
Department of General Medicine, Nootan Medical College and Research Centre, Visnagar, Gujarat, India.

 

Hardik P Modi
Department of General Medicine, Nootan Medical College and Research Centre, Visnagar, Gujarat, India.

 

Jaysinh Rathva
Department of Respiratory Medicine, Nootan Medical College and Research Centre, Visnagar, Gujarat, India.

 

Rajan Chaudhary
Department of General Medicine, Nootan Medical College and Research Centre, Visnagar, Gujarat, India.

 

Jitendra Patel
Department of Physiology, GMERS Medical College, Vadnagar, Gujarat, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrni/v6/2394

Antiviral Potential of Milk Proteins and Peptides against Zoonotic Viruses | Chapter 12 | An Overview of Disease and Health Research Vol. 2

In addition to its well-established nutritional value, milk is increasingly recognized as a rich source of bioactive compounds with potential health-promoting properties. Among these, milk proteins and their derived peptides have attracted growing scientific interest due to their multifunctional biological activities. Notably, recent studies have identified potent antiviral effects associated with these components, suggesting a promising role in the prevention and control of zoonotic viral diseases.

 

Despite a growing body of research exploring milk’s broader bioactivities, the specific antiviral potential of milk-derived peptides remains relatively underexplored in the literature. This gap represents a critical opportunity to advance knowledge in the fields of virology, nutrition, and One Health, particularly in the context of emerging infectious diseases.

 

This review aims to consolidate current scientific evidence on the antiviral properties of milk-derived proteins and peptides, with a particular focus on zoonotic viruses and the underlying mechanisms of action. To achieve this, a comprehensive literature search was conducted using scientific databases Relevant peer-reviewed articles published in English were identified through the application of specific keywords and Boolean operators. The selection process involved screening titles, abstracts, and full texts to ensure alignment with the scope of the review. These mechanisms may include inhibition of viral entry and attachment, interference with the replication processes, or direct viral inactivation through interactions with viral membranes.

 

Given their broad-spectrum activity and favourable safety profile, milk-derived antiviral peptides represent a compelling area for further research and development. Their potential applications span human and veterinary medicine, the nutraceutical sector, and the dairy industry—especially in a post-pandemic world where innovative antiviral strategies are urgently needed.

 

Author (s) Details

Maria Isabel Santos
Research in Veterinary Medicine (I-MVET), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal and Veterinary and Animal Research Centre (CECAV), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal.

 

Tomás Moita
Faculty of Veterinary Medicine, Lusófona University, Lisbon University Center, Lisbon, Portugal.

 

Laurentina Pedroso
Research in Veterinary Medicine (I-MVET), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal and Veterinary and Animal Research Centre (CECAV), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal.

 

Ana Lima
Research in Veterinary Medicine (I-MVET), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal and Veterinary and Animal Research Centre (CECAV), Faculty of Veterinary Medicine, Lusófona University, Lisbon University Centre, Portugal.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/aodhr/v2/5545

 

Iron and Immunity in Cancer: From Molecular Mechanisms to Clinical Applications | Chapter 12 | Medical Science: Recent Advances and Applications Vol. 4

Iron is essential for numerous biological functions, including oxygen transport, energy production, and immune defense. In cancer patients, however, iron deficiency and iron overload can adversely affect disease progression and treatment outcomes. Iron deficiency impairs immune responses and can reduce the effectiveness of immunotherapies such as immune checkpoint inhibitors (ICIs). Conversely, excess iron promotes tumor growth, oxidative stress, and immune evasion, creating a microenvironment that reduces treatment efficacy. This review highlights the dual role of iron metabolism in cancer, examining how altered iron levels affect immune cell function, tumor progression, and therapeutic responsiveness. Emerging preclinical and clinical data suggest that personalized iron modulation may improve outcomes through supplementation in deficient patients or iron-reducing strategies in cases of overload. Moreover, combining iron-targeted approaches with immunotherapy could enhance anti-tumor efficacy by synergistically restoring immune competence and targeting tumor vulnerabilities. These findings support the integration of iron assessment and individualized management into routine oncology practice. Further clinical studies are needed to optimize iron-based interventions and to explore their synergy with existing cancer therapies, particularly immunotherapy.

 

Author (s) Details

Omar Badran
Department of Oncology, Emek Medical Center, Afula 1834111, Israel and Faculty of Medicine, Technion Integrated Cancer Center, Technion, Haifa 3525422, Israel.

 

Idan Cohen
Department of Oncology, Emek Medical Center, Afula 1834111, Israel.

 

Gil Bar-Sela
Department of Oncology, Emek Medical Center, Afula 1834111, Israel and Faculty of Medicine, Technion Integrated Cancer Center, Technion, Haifa 3525422, Israel.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/msraa/v4/5353

Intersections of Neurobiology and Oncology: Foundations and Frontiers in Cancer Neuroscience | Book Publisher International

Cancer neuroscience encompasses a multidisciplinary field that investigates the intricate interactions between the nervous system and cancer biology, particularly within the context of tumorigenesis, metastasis, and therapeutic responses. This burgeoning area of research explores the bidirectional communication between cancer cells and neural tissues, ranging from the molecular and cellular mechanisms to the clinical implications for cancer diagnosis, prognosis, and treatment. Key aspects of cancer neuroscience include elucidating the role of neurotrophic factors, neurotransmitters, and neuropeptides in tumor growth and metastasis, as well as characterizing the neural circuits and microenvironmental cues that influence cancer progression. Additionally, cancer neuroscience encompasses the study of neuroinflammatory responses, neuroimmune interactions, and neuroplasticity in the context of cancer-related neurologic complications and therapeutic resistance. Moreover, advances in neuroimaging technologies and computational modeling have enabled the visualization and analysis of neural networks and tumor dynamics, offering insights into the spatiotemporal dynamics of cancer spread and response to therapy. Integrating knowledge from neuroscience, oncology, and neurology, cancer neuroscience holds promise for the development of innovative diagnostic biomarkers, targeted therapies, and personalized interventions to combat cancer progression and improve patient outcomes. Recent discoveries in cancer neuroscience have shed light on the intricate interplay between neural processes and cancer progression. For instance, researchers have identified specific neural circuits implicated in tumor growth and metastasis, unveiling potential targets for therapeutic intervention. Additionally, studies have elucidated the role of neuroinflammation in promoting cancer cell proliferation and invasion, offering new insights into the complex interactions between the nervous and immune systems in tumorigenesis. These findings underscore the importance of understanding the neural mechanisms underlying cancer development and highlight the potential for novel therapeutic strategies targeting the nervous system to combat cancer progression. Cancer neuroscience research employs a diverse range of methodologies to investigate the complex relationship between neural processes and cancer. Neuroimaging technologies, such as functional magnetic resonance imaging (fMRI) and positron emission tomography (PET), are commonly utilized to visualize brain activity patterns associated with cancer progression and treatment responses. Additionally, computational modeling techniques enable researchers to simulate and analyze neural network dynamics, aiding in the interpretation of complex data and the prediction of tumor behavior. Moreover, molecular and cellular approaches are employed to study the molecular mechanisms underlying neurocancerogenesis, offering valuable insights into the cellular pathways involved in tumor initiation and growth. Overall, the interdisciplinary nature of cancer neuroscience research combines advanced methodologies from neuroscience, oncology, and computational biology to unravel the intricate connections between the nervous system and cancer. Cancer neuroscience research is significantly impacting clinical practices and the development of new therapies by providing deeper insights into the underlying mechanisms of cancer progression and treatment responses. Neuroimaging technologies, such as functional MRI and PET, allow clinicians to visualize and monitor brain activity patterns associated with cancer-related symptoms, enabling more accurate diagnosis and treatment planning. Additionally, molecular and cellular studies in cancer neuroscience have identified novel therapeutic targets and biomarkers for personalized medicine approaches, facilitating the development of targeted therapies and immunotherapies. Furthermore, the integration of neurocognitive assessments into cancer care has improved our understanding of the cognitive effects of cancer and its treatments, leading to the development of supportive care interventions aimed at mitigating cognitive impairments and improving quality of life for cancer patients. Moreover, computational modeling techniques are being used to predict treatment outcomes and optimize treatment regimens, guiding clinicians in making more informed decisions tailored to individual patient characteristics. The insights gained from cancer neuroscience research are translating into tangible clinical benefits, including improved diagnostic accuracy, targeted therapies, personalized treatment approaches, and enhanced supportive care for cancer patients. This interdisciplinary field is bridging the gap between basic research and clinical practice, ultimately leading to better outcomes for cancer patients and transforming the landscape of cancer care. While cancer neuroscience holds promise for revolutionizing cancer care, it is not without its challenges and limitations. One significant challenge is the complexity of the neural mechanisms involved in cancer progression, which often span multiple biological scales and pathways. Understanding these intricate interactions requires interdisciplinary collaboration and advanced methodologies, which may not always be readily available or easily accessible. Additionally, there are technical limitations associated with neuroimaging techniques and computational modeling approaches used in cancer neuroscience research. For example, neuroimaging modalities may have limited spatial or temporal resolution, making it challenging to capture dynamic changes in neural activity associated with cancer progression. Moreover, computational models may oversimplify the complexity of neural networks or lack validation against clinical data, limiting their predictive power and clinical utility. Furthermore, the heterogeneity of both cancer and neurological diseases poses a significant challenge in cancer neuroscience research. Tumor cells and neural tissues can exhibit diverse molecular profiles and responses to treatment, making it difficult to develop generalized therapeutic strategies. Moreover, variations in patient demographics, genetic backgrounds, and environmental factors further complicate the interpretation of research findings and the translation of discoveries into clinical practice. While cancer neuroscience holds great promise for improving cancer diagnosis, treatment, and outcomes, addressing these challenges and limitations is essential for advancing the field and realizing its full potential. Continued research efforts aimed at overcoming these obstacles will be critical for driving innovation and innovation in cancer neuroscience and ultimately improving patient care. This book provides an overview of the diverse facets of cancer neuroscience and highlights its potential impact on understanding and managing cancer-related neurologic disorders.

Author(s) Details:

Tahmineh Azizi,
Department of Biology, University of Missouri-St. Louis, USA.

Please see the link here: https://stm.bookpi.org/INOFFCN/article/view/14252

Clinical-epidemiological Profile of Outpatients with Mild to Moderate Covid-19 Intensity, in the South of Mexico City | Chapter 9 | Current Progress in Medicine and Medical Research Vol. 9

Objective: Report the dispassionate-epidemiological profile of outpatients accompanying mild to moderate intensity COVID-19, that was carried out in the South of Mexico City. The dossier were obtained through a pre-coded inquiry, designed only for this study, the labeling card was taken and sociodemographic variables were calculated, non-pathological biography (transmission machine), pathological personal history (comorbidities diabetes mellitus, arterial hypertension, prior lung study of plants, cancer, HIV, AIDS, asthma, allergy, corpulence, cardiovascular disease, hot, alcoholism) Current Condition, Signs and symptoms, workshop and cabinet studies.Materials and Methods: This is a potential, cross-sectional, observational, sole-center study of a series of sufferers with dispassionate data of upper and lower respiring tract contamination and positive PCR for SARS-CoV-2. The study population incorporated 66 patients the one met the inclusion tests, carried out by telemedicine to a first contact commission specializing in catching diseases, attended from March 10, 2020 to January 31, 2021. The facts was analyzed in a mathematical package using SPSS 23.0.Results: 66 cases who join the criteria established for disease were attended. The period of January 2021 saw the maximal number of patients, who wanted medical consideration, 6.5 days (range 1 to 12 days) after starting the affliction. The median age was 48 age (range 10 to 80 years), 53% were female, 26% had type 2 diabetes mellitus, 23% with arterial hypertension, 7% former lung affliction, 4% suffered from hypothyroidism, 24% beneficial smoking, 21% positive alcohol abuse, 39% had obesity, 17% were hypersensitive. The clinical characteristics, ultimate prevalent was cough in 76%, understood by headache 73% and myalgia 71%.Conclusions: Patients with comorbidities, either men or girls in the fifth decade of history, are of great significance for the evolution, exceptionally when they are carriers of immunosenescence in the cases of those over 60 years adult, or the immune order is immunocompromised as it is. the case of patients with DM2 and even more when they have as well one comorbidity that wrong have a proinflammatory state and attenuation of the innate invulnerable respons

Author(s) Details:

María de Lourdes Patricia Ramírez Sandoval,
Mexican Institute of Social Security and Private Medicine, Mexico.

Alejandro Roldan Vences,
Mexican Social Security Institute, Mexico.

Jorge Eduardo Macias Garza,
National Institute of Pediatrics, Mexico.

Maribel Adriana Varela Ramirez,
Vereda del Colibri, Colonia San Andrés Totoltepec, Mayor Tlalpan, Code Postal-14400, Mexico.

Please see the link here: https://stm.bookpi.org/CPMMR-V9/article/view/11693

Potential Role of Punica Granatum (Pomegranate) in Management of COVID-19: A Review | Chapter 8 | Novel Aspects on Pharmaceutical Research Vol. 3

 Viral contaminations suppress invulnerable system of the host. SARS-CoV-2, Just like other energetic infections diminish the host immunity. A powerful immune system is the key to care from virus and additional pathogens. Severe cases admitted to the icu showed high level of supporting-inflammatory cytokines that enhanced the disease asperity. Antioxidant medications are submitted as a current course of treatment for subjects who have the SARS-CoV-2 virus.It raises glutathione and oxygen levels, that strengthens the immune reaction. The results include a decrease in the amount momentary required for mechanical airing, the prevention of diversified organ dysfunctions, a smaller hospital stay, and a lower mortality rate.  Immune timbre is the only way of managing of the immune structure. Punica Granatum has been used as a usual medicine for point in time. The components of this plant are famous for its rich invulnerable-regulation, antagonistic-inflammatory, and antioxidant benefits in specially in respiring disorders. Many of the study results are based on artificial and cell-located assays. It necessitates further confirmation of in vivo productiveness through human clinical tests.

Author(s) Details:

Rabiea Bilal,
Department of Pharmacology, CMH LMC & IOD, NUMS, Pakistan.

Please see the link here: https://stm.bookpi.org/NAPR-V3/article/view/10883

Applications of Traditional Medicines in Prevention and Treatment of the Diseases of Humankind | Chapter 1 | Current Overview on Pharmaceutical Science Vol. 9

 Globally, spreading afflictions have been a danger to public's well-being. The use of newly found antiviral and medicine powers has allowed us to favorably treat the plurality of afflictions due to our merciless works and research.  Unfortunately, the talent of microorganisms to adapt and convert over period leads to medicine and antiviral resistance. There are many troubles in doctoring contaminations, such as the microorganisms' failure to respond to the healing agents, that has raised the risk of difficulties, chronic contaminations, and stoppable fatalities. As a result, a multidisciplinary approach and cooperation are necessary to expand more potent, persuasive, and adjustable analyses to prevent and destroy two together traditional and new diseases. Natural medicine has currently showed allure effectiveness in acting a sort of diseases. The majority of drug powers now in use maybe copied back to unrefined products by some means, shape, or form. Because many water have still to be surveyed and resolved, the complete potential of natural output has still expected realized. This entails continuous support for research and reasoning of ancient situation plans in consideration of fully exploit their potential and use bureaucracy a suggestion of choice or basic therapy.

Author(s) Details:

Syed A. A. Rizvi,
College of Biomedical Sciences, Larkin University, Miami, FL, USA.

George P. Einstein,
College of Medicine, University of Science, Arts & Technology, Olveston, Montserrat.

Orien L. Tulp,
College of Medicine, University of Science, Arts & Technology, Olveston, Montserrat.

Frantz Sainvil,
College of Medicine, University of Science, Arts & Technology, Olveston, Montserrat.

Rolando Branly,
Physical Sciences Department, Broward College, Davie, FL, USA.

Please see the link here: https://stm.bookpi.org/COPS-V9/article/view/10166

Advances in Treating Chronic Disease| Book Publisher International

 Since ancient times, in the medical field, people have taken advantage of natural substances to cure diseases. Today, modern medicine is constantly developing, inheriting from the ancients to continue to conduct new research and produce effective treatment products for several diseases that are considered chronic today.

The compositions mentioned in the book have successfully treated a number of supposedly chronic diseases, such as cirrhosis and hepatocellular carcinoma caused by HBV and HCV infections; increased antibodies against COVID-19 in immunocompromised patients, infertility due to orchitis, the testicles are unable to produce spermatozoon, help the testicles complete five successive stages: (1) spermatogonia, (2) primary spermatocytes, (3) secondary spermatocytes, (4) spermatids, and (5) spermatozoon; protecting the fetus, and helping the fetus to develop to full term in a uterus with multiple fibroids. The selective compositions act on the patient's immune system, helping the body to resist harmful effects from the environment. Thanks to the natural substances: Flavonoids; Ascorbic Acid; Pyridoxal phosphate; Pregnenolone, they act as anti-inflammatory agents, enzymes that catalyze the body's chain reactions, as well as natural hormones. They have corrected chronic inflammatory disorders, tumors that grow out of control, causing a number of dangers to the patient's health. Research has shown that flavonoids and vitamins such as Ascorbic Acid, Pyridoxal phosphate, and Pregnenolone mentioned in this book have the necessary biological activity. They have a high impact potential, help the body to regulate, inactivate viruses, dissolve inflammatory tissue, prevent and destroy cancer cells at an early stage.

With practical evidence, the book will give readers an overview of the potential that needs to be discovered from nature to serve human life.

Author(s) Details:

Nguyen Thi Trieu,
Clinical Drug Research and Development Department under Saigon Biopharma Company, Vietnam.

Tran Minh Duc,
Clinical Drug Research and Development Department under Saigon Biopharma Company, Vietnam.

Tran Minh Cam Tu,
Clinical Drug Research and Development Department under Saigon Biopharma Company, Vietnam.

Please see the link here: https://stm.bookpi.org/ATCD/article/view/8972

Immune Mechanistic Interventions for Immune Modulation and Boosting | Book Publisher International

 The human immune system is a sophisticated system with a mammoth challenge ahead of it: deciphering its numerous paths. The ability to distinguish between their own cells and foreign cells is a key feature of this immune system. The immune system is made up of a variety of cells, tissues, and organs. Primary cells are made in the bone marrow and thymus, and secondary lymphoid organs are made in the lymph node, spleen, and tonsils, and circulate throughout the body for the rest of one's life. Phagocytic cells, such as macrophages, monocytes, and neutrophils, are one of the immune system's key barriers, engulfing microbial cells or foreign substances and digesting and excreting them. It is critical to comprehend and unravel the process that protects the human body from pathogen attack. The immune system's developed weapons against pathogen attack are revealed. Immune boosters derived from natural resources such as plants and marine sources play a critical role in boosting the immune system and, as a result, raising the body's army against a slew of pathogenic microbial foes. The goal of this review is to figure out how the mechanisms work and how important they are in the body's defence. Along with looking into potential phyto- and marine-based immune boosters that could help increase the body's defence mechanisms.

Author(s) Details

A. Mary Shamya
Centre for Drug Discovery and Development, Sathyabama Institute of Science and Technology, Chennai Tamil Nadu, India.

Jerrine Joseph
Centre for Drug Discovery and Development, Sathyabama Institute of Science and Technology, Chennai Tamil Nadu, India.

Rajasekar Thirunavukkarasu
Centre for Drug Discovery and Development, Sathyabama Institute of Science and Technology, Chennai Tamil Nadu, India.

Radhakrishnan Manikkam
Centre for Drug Discovery and Development, Sathyabama Institute of Science and Technology, Chennai Tamil Nadu, India.

Wilson Aruni
Sathyabama Institute of Science and Technology, Chennai – 600119, Tamil Nadu, India and School of Medicine, California University of Science and Medicine, CA, USA and Musculoskeletal Disease Research Laboratory US, Department of Veteran Affairs, Loma Linda, CA, USA.

View Book:- https://stm.bookpi.org/IMIIMB/article/view/6316

Research on Surgery and Chronic Stress Ultimately Leading to Major Health Risks | Chapter 9 | Research Trends and Challenges in Medical Science Vol. 10

 This article discusses how surgery, regardless of age or organ, can become a major health issue. In general, about 50-60% of surgical patients experience mild/moderate/severe psychobiological illness in the future for a long time due to a concern that he/she (1:3) has lost a part of his body within an unhealed or prolonged healing phase. As a result, certain neuropsychiatric symptoms like anxiety, pain, emotion, and depression progressively become a part of their everyday lives, ultimately leading to chronic stress (about 10%) and significant health risks in the 4-6 years following surgery. Chronic stress is mostly caused by a poor socioeconomic situation and the effects of surgery.

Author (s) Details

Tarit Kanti Ghosh
Internal Medicine & Neurology, Clinical Neurology, University College of London UK and Research Clinical Neuroscience, The University of Melbourne, Australia

View Book :- https://stm.bookpi.org/RTCMS-V10/article/view/712