Redness is a natural response to fabric damage or infection, begun by the immune order to facilitate repair and healing. Nonsteroidal antagonistic-inflammatory drugs (NSAIDs) are widely recognized for their antagonistic-inflammatory, pain remover, and fever-reducing belongings. In addition to treating swelling, pain, and fever, NSAIDs are frequently used to treat severe and chronic angering conditions such as migraines, capacity to sense flavor, migraine symptoms, and arthritis. Low side effects of NSAIDs include sickness in stomach, dyspepsia, GI bleeds or ulcers, extreme liver enzymes, diarrhea, constipation, epistaxis, problem, dizziness, rash, fluid retention, and extreme blood pressure. The digestive system's exposure limits their application. This review investigate the potential of -COOH group protection to mitigate gastrointestinal toxicity, intending the development of NSAID prodrugs through ester linkage accompanying antioxidants. The envisioned prodrugs aim not only to address the digestive system's concerns but again to exhibit synergistic conduct, expanding the therapeutic potential of NSAIDs.
Author(s) Details:
Manoj Kumar Sahoo,
Department
of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.) - 495009, India.
Nidhi
Agrawal,
Department
of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.) - 495009, India.
Meenakshi Jaiswal,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur
(C.G.) - 495009, India.
S. K. Lanjhiyana,
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur
(C.G.) - 495009, India.
Please see the link here: https://stm.bookpi.org/ACPR-V3/article/view/12760
No comments:
Post a Comment