Analyzing the Histopathological Spectrum of Central Nervous System Tumours at a Tertiary Care Centre: A One Year Prospective Study | Chapter 3 | Advanced Concepts in Medicine and Medical Research Vol. 10

This phase aims to analyse the histopathological spectrum of Principal nervous system (CNS) tumours irrespective adult in a single organization. CNS tumors are a distinct and heterogeneous group of neoplasms that involve both mild and malignant neoplasms. Because of their changing presentation and coinciding morphological features, these tumors are disputing to diagnose. Immunohistochemistry acquired immune deficiency syndrome in the resolution of demonstrative challenges in challenging instances. The age distribution of CNS tumours is pronounced to be bimodal. Men are involved more frequently, meningiomas being irregularity.This  one period prospective study was conducted, at the area of pathology, ASRAM from 2016 to 2017. Neurosurgical samples were formalin-fixed and paraffin-embedded and tainted with Haematoxylin and eosin. Immunohistochemical stones were used in specific cases like S-100, CD-45, etc. In our hearing, 72 brain neoplasms were checked.The findings accompanied that  Neuroepithelial tumours (25) were most common, followed by meningothelial tumours (22), tumours of sellar inception(12), tumours of cranial and paraspinal nerves(5), metastatic tumours(4) and so forth (4). The current study emphasizes the histological variability of CNS tumors indifferent age groups. The greatest occurrence of CNS tumors was observed in the fourth to having five of something decade. Afterwards the age of 40, meningiomas and astrocytomas were prevalent tumors. Among astrocytomas, GBM was ultimate prevalent. Immunohistochemistry was beneficial in difficult instances.

Author(s) Details:

Gudeli Vahini,
Department of Pathology, Asram Medical College, Elluru, Andhra Pradesh, India.

K. Shilpa Madhuri,
Department of Pathology, Asram Medical College, Elluru, Andhra Pradesh, India.

B. A. Ramakrishna,
Department of Pathology, Asram Medical College, Elluru, Andhra Pradesh, India.

Sumakaza,
Department of Pathology, Asram Medical College, Elluru, Andhra Pradesh, India.

K. Rammurthy,
Department of Pathology, Asram Medical College, Elluru, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/ACMMR-V10/article/view/12817