DNA Damage in Peripheral Blood Mononuclear Cells and Neutrophils of Dairy Cows during the Transition Period: Experimental Investigation | Chapter 14 | Advanced Research in Biological Science Vol. 5

 The purpose concerning this study was to examine the apoptotic process in peripheral ancestry mononuclear cells (PBMC) and polymorphonuclear neutrophil leukocytes (PMN) in creamery cattle all the while the transition ending. This period is from marked changes in the endocrine rank of the animals that are much more moving than at any different time in the removal of liquid gestation era, and by a reduction in feed consumption when nutrient demand for the evolving conceptus and the impending lactogenesis are increasing. Blood samples were captured from four dairy cows three weeks before discharged parturition (wk -3), all the while parturition (ww 0), and three weeks subsequently parturition (wk +3). The meteor test was used to assess the DNA damage of PBMC and PMN utilizing visual notch (arbitrary wholes). Undamaged DNA remained in the gist (score 0), while broken DNA well-traveled from the core to the anode, create a comet tail (cut 1-4).  Significantly higher scores in PBMC were stated at wk 0 and wk +3 compared to PMN, in spite of no significant changes in scores in either container type across the study period. It has happened suggested that the apoptotic rate of PBMC is faster than that of PMC all along the transition ending.

Author(s) Details:

Mohamed Tharwat,
Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt and Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Saudi Arabia.

Shin Oikawa,
Veterinary Herd Health, Department of Veterinary Medicine, School of Veterinary Medicine, Rakuno Gakuen University, Japan.

Please see the link here: https://stm.bookpi.org/ARBS-V5/article/view/12587