Wednesday, 22 November 2023

Determination of Controlled Local Hyperthermia and Magnetic Hyperthermia of Cancer Diseases in Skin | Chapter 14 | Advanced Concepts in Medicine and Medical Research Vol. 5

 This stage discusses about regulated Local Hyperthermia and Magnetic Hyperthermia of Surface (Skin) Cancer Diseases. Index of morbidity and fatality conditioned by malignancies in all world is increasing forever. Early diagnostics is instead difficult and plurality of patients address nursing homes because of statement cancers, when they need combined resection, radiation and drug remedy and complex treatment. Average capacity of hematite and magnetite micro and Nano powders and poly dispersity index, zeta potential and distribution of pieces were studied. Analysis accompanied that average size of the got particles for magnetite is 740.9 nm, for hematite atoms 30 - 35 nm. Alternate current feed source was devised for hyperthermia. Based on the objectives' necessities, U-type Mn Zn material magneto conductors were preferred. Glass test tubes containing magnetite or hematite suspensions were introduced into gaps that were cut to 10.0 and 8.0 mm in width. A succession of experiments conducted at various frequencies and field intensities disclosed that a more potent design with a repetitiveness of up to 10 megahertz was necessary for effective drawing hyperthermia therapy in order to reach the hotness of 43°-45°C, which is necessary for the full incitement of Neel and Brown mechanisms granular. At the next stage, on the basis of exploratory material the anti- tumor mono-therapeutic effect of hyperthermia and allure adjuvant operation in poly chemotherapeutic treatment was presented for one use of a device generated by us “LEZI”. Results of visual notes are proved for all three mammals, on the basis of calculations made later three, seven and ten sessions. As a result of the experiment it was proved that in all animals (outbred light mice, 3 months traditional) inhibition of tumor growth was established and intra cyst necrosis was grown, while after 7 and 10 gatherings tumors were ulcerated, that refers to positive effect of the experiment (Conclusion of Pathologic anatomical Laboratory “PATGEO”, Tbilisi, Georgia).

Author(s) Details:

Zviad Kovziridze,
Department of Chemical and Biological Technology, Technical University of Georgia, Tbilisi, Georgia.

Paata Khorava,
Department of Chemical and Biological Technology, Technical University of Georgia, Tbilisi, Georgia.

Nunu Mitskevich,
Department of Chemical and Biological Technology, Technical University of Georgia, Tbilisi, Georgia.

Please see the link here: https://stm.bookpi.org/ACMMR-V5/article/view/12566

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