Costus igneus and allure secondary metabolites have happened widely evaluated and used to treat subjects with diabetes with metabolic condition. Recent evidence submitted that non-alcoholic fatty liver affliction (NAFLD) and diabetes associated metabolic condition were the important risk factors for hepatocellular abnormal growth in animate being (HCC). So, herbals with insulin sensitizing characteristics have a promising duty in the control of metabolic syndrome and tumor. This study was conducted to evaluate the artificial anticancer activity of the ethanolic extract of Costus igneus leaves against hepatocellular abnormal growth in animate being (HepG2) cells. Artificial cytotoxicity activity (MTT assay) of the plant extract leaves was acted with eight different concentrations (1000 to7.8µg/ml) and the allotment of viability was premeditated from the graph. The aggregation required for a 50% being inhibition (IC 50) was calculated as 62.5µg/ml. Still, 74.57% and 22.65% of cell animation were produced apiece concentration of 7.8µg/ml and 1000µg/ml individually. These results observed the cytotoxic activity of ethanolic extract of Costus igneus leaves and confirmed the potential role of Costus igneus phytochemical possessions against hepatocellular carcinoma.
Author(s) Details:
Glory Josephine I.,
Department
of Pharmacology, Sree Balaji Medical College & Hospital, Bharath Institute
of Higher Education and Research (BIHER), Chennai 600044, India.
Please see the link here: https://stm.bookpi.org/ACPR-V3/article/view/12700
No comments:
Post a Comment