Introduction: Prostate cancer has been the most common non-cutaneous malignancy in men and now accounting for one-quarter of all such cancers. Use of Trans Rectal Ultrasonography (TRUS) in men with an abnormal PSA and/or digital rectal examination acting as a guide to direct prostate biopsies will lead to a decrease in the number of early deaths.
Materials and Methods: It is a prospective observational study.
All the patients attending the Urology clinics or emergency services with LUTS
and with a suspicion of Ca prostate on DRE or serum PSA were enrolled in the
study. TRUS-guided biopsy was done in all study patients for abnormality on DRE
and or an elevated serum PSA level. The statistical analysis was executed by
SPSS version 20. Categorical variables were analyzed with "Chi-square
test".
Results: In the present study, of 95 men, 53 men underwent 10-core
biopsy and 42 men underwent 16-core biopsy. Among 95 patients subjected to TRUS
guided prostate biopsy, prostatic adenocarcinoma was detected in 31 (32.6%),
High-grade PIN in 12 (12.62%), fibroadeno leiomyomatous hyperplasia in 30
(31.57%), fibroadeno leiomyomatous hyperplasia with chronic prostatitis in 5
(5.20%) and chronic prostatitis in 15 (15.78%).
Conclusion: The cancer detection rate is high when abnormalities
are found in both DRE and PSA compared to elevated PSA alone (70% vs.15%). The
detection rate with 16-core TRUS guided biopsy is significantly higher than
10-core biopsy (54.76% vs. 15.09%, P value 0.0037).
Author
(s) Details
P. Usha Kiran
Department of Biochemistry, TMMC & RC, TMU, Moradabad, UP, India.
S. Venkata Krishna
Dr. SVK Kidney Care & HOLEP Centre, Rajahmundry, AP, India.
Please see the book here:- https://doi.org/10.9734/bpi/nvmms/v10/3069
No comments:
Post a Comment