Overview of Flow Cytometry Techniques for Immunophenotyping in B-Cell Lymphoproliferative Disorders | Chapter 5 | Achievements and Challenges of Medicine and Medical Science Vol. 7

B-cell lymphoproliferative disorders (BCLPDs) encompass a diverse range of neoplasms with immunophenotypic profiles. This review discusses the classification of BCLPDs based on flow cytometric immunophenotyping, focusing on markers such as CD5, and CD10. Key subtypes, including CLL, MCL, and DLBCL, are analyzed for diagnostic and prognostic insights. Advanced flow cytometry techniques aid in subtype differentiation, guiding personalized treatment approaches and improving outcomes. Global variations and diagnostic challenges are also highlighted, supporting a comprehensive understanding of BCLPDs.

 

 

Author (s) Details

 

B L T Balasuriya
Department of Haematology, Sri Jayewardenepura General Hospital, Thalapathpitiya, Nugegoda, Sri Lanka.

 

C S Moonesinghe
Department of Pathology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

 

S S N Fernando
Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

 

T D C P Gunasekara
Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

 

S Jayakody
Department of Community Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

 

C C Kariyawasan
Department of Haematology, Sri Jayewardenepura General Hospital, Thalapathpitiya, Nugegoda, Sri Lanka.

 

Please see the book here:- https://doi.org/10.9734/bpi/acmms/v7/3477