Assessment of Microvascular Complications in Females with Type-2 Diabetes Mellitus through Biochemical Evaluation and Anthropometric Measurements | Chapter 1 | Recent Developments in Chemistry and Biochemistry Research Vol. 9

Background: Diabetes mellitus currently affects millions of people worldwide and projections for the future are alarming.

Objective: This study highlights the role of the biochemical parameters in the prediction of microvascular complications in Type 2 diabetes and non-diabetes female subjects.

Materials and Methods: The present study was conducted in R L Jalappa Hospital attached to Sri Devaraj Urs Medical College a constituent of Sri Devaraj Urs Academy of Higher Education and Research, Kolar. Randomly selected 45 female type 2 diabetes and non-diabetes subjects with the age group of 45-55 years attending the medicine outpatient department for a period of three months were included in the study. Anthropometric and biochemical parameters were analyzed by standard methods.

Results: Among the analysed variables in this study, we observed mean values of obesity index (55.13±6.94, 50.20±11.62), Diastolic BP (78.35±11.08, 78.62±7.91), Fasting Blood Sugar (147±65.75, 90.71±30.53), HbA1c (9.22±2.48, 6.24±1.69), Serum Creatinine (0.84±0.32, 0.65±0.12), urine creatinine (57.73±51.95, 97.60±178.84), HDL (36.44±8.48, 43.46±10.65) and LDL (100.39±40.65, 115.20±24.02) were significantly elevated in female diabetic subjects compared to non diabetes subjects.

Conclusion: The anthropometric measures did not significantly differ between diabetes and non-diabetes. In this study, we observed 26.6% of nephropathy, 13.3% of retinopathy and 6.6% of neuropathy in diabetes females. However, non-diabetic female subjects showed higher significant TC and LDL-C levels. This suggests that those above the age of 45-year females require a comprehensive evaluation of anthropometric and biochemical parameters to avoid micro and macrovascular complications.

 

Author (s) Details

Munilakshmi U
Department of Biochemistry, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.

 

Shashidhar KN
Department of Biochemistry, Sri Devaraj Urs Medical College, Tamaka, Kolar, India.

 

Harish R
Department of Biochemistry, Haveri Institute of Medical Sciences, India.

 

Madhavi Reddy
Clinical Nutrition and Dietetics, Sri Devaraj Urs Medical College, India.

 

Lakshmaiah V.
Department of Medicine, Sri Devaraj Urs Medical College, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/rdcbr/v9/2528