Peptic ulcer disease (PUD) refers to the condition that causes ulcers in the lining of the digestive tract. A common condition in the world, Peptic Ulcer condition is sometimes referred to as stomach ulcers or peptic ulcers. This review study covers the pathophysiology, aetiology, medical therapy, diagnosis, symptoms, and signs of Peptic Ulcer Disease (PUD). The word "peptic" comes from the hormone pepsin, which is essential in causing mucosal breakdown. PUD is caused by a defect in the mucosa of the stomach or duodenum that extends beyond the muscularis mucosa. PUD is the consequence of an imbalance between the aggressive and defensive elements impacting the mucosa, which occurs after gastric mucosal lesions. Peptic ulcer disease (PUD) is a widespread ailment affecting 5–10% of the world's population, with notable racial and regional variations. As a result of an imbalance between the aggressive and defensive elements impacting the mucosa, comes gastric mucosal injuries. Millions of healthcare dollars are frequently spent on treating gastric ulcers, which are a typical clinical presentation in the US. Esophageal Ulcer and Duodenal Ulcers are also two common types of Peptic Ulcer that are affecting the global population. The most common cause of upper gastrointestinal bleeding in the Western world is bleeding from peptic ulcers (PUs). High rates of morbidity, mortality, and medical costs are linked to it. To learn more about the best course of action for treating peptic ulcer disease (PUD), further randomized controlled trials are required.
Author(s) Details:
Yash Srivastav,
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.
Mohd. Faijan Mansoori,
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.
Abdul Hameed,
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.
Afreen Hashmi,
Babu Banarasi Das Northern India Institute of Technology, Lucknow, U.P, India.
Mohd. Imtiyaz Ahmad,
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.
Please see the link here: https://stm.bookpi.org/ACPR-V8/article/view/14045
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