Background and Aim: Immune thrombocytopenia (ITP) does not
commonly coexist with Crohn’s disease (CD). Therefore, this review aimed to
investigate studies involving patients with comorbid ITP and CD.
Methods: A literature search and review was conducted for
the patients with comorbid ITP and CD, excluding those with drug or
vaccination-induced ITP.
Results and Conclusion: Among 26 cases included in this
review, ITP, CD, and comorbid ITP and CD were initially diagnosed in 8, 10, and
8 cases, respectively. The onset of ITP might be associated with CD aggravation
in some cases. Although standard therapies in comorbid ITP and CD cases were
glucocorticoids, intravenous immunoglobulin, biologics, and splenectomy, bowel
resection for CD might achieve ITP remission in some cases. No fatalities were
reported among 26 cases.
Author(s) Details:
Toru Shizuma,
Department of Physiology, Tokai University School of Medicine, 143,
Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
Please see the link here: https://stm.bookpi.org/ANUMS-V8/article/view/13523
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