Concurrent Immune Thrombocytopenia and Crohn’s Disease: A Review of Reported Cases |Chapter 4 | An Overview of Disease and Health Research Vol. 5

 

Background and Aim: The coexistence of immune thrombocytopenia (ITP) and Crohn’s disease (CD) is not common. This review investigated studies involving cases of concurrent ITP and CD.

 

Methods: A literature search and review of studies on patients with comorbid ITP and CD, excluding those with drug- or vaccination-induced ITP, was conducted.

 

Results: Of the 32 cases included in this review, 17 (53.1%) were men, and 15 (46.9%) were women. Ten (31.3%) patients were initially diagnosed with ITP, and 12 (37.5%) with CD. Meanwhile, 10 (31.3%) patients were simultaneously diagnosed with ITP and CD. The development of ITP might be associated with CD aggravation in some cases. The standard therapeutic approaches for comorbid ITP and CD were glucocorticoids, intravenous immunoglobulin, biologics, and splenectomy. However, ITP remission might be achieved with bowel resection for CD. No fatalities were reported.

 

Conclusion: In the reported cases of comorbid ITP and CD, no clear trends were observed regarding sex and preceding disease. Nevertheless, the prognosis in these cases can be favourable.

 

Author(s) Details

 

Toru Shizuma
Department of Physiology, Tokai University School of Medicine, 143, Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

 

Please see the book here:- https://doi.org/10.9734/bpi/aodhr/v5/6056

 

Comorbid Cases of Immune Thrombocytopenia and Crohn’s Disease | Chapter 10 | Advancement and New Understanding in Medical Science Vol. 8

Background and Aim: Immune thrombocytopenia (ITP) does not commonly coexist with Crohn’s disease (CD). Therefore, this review aimed to investigate studies involving patients with comorbid ITP and CD.
 
Methods: A literature search and review was conducted for the patients with comorbid ITP and CD, excluding those with drug or vaccination-induced ITP.
 
Results and Conclusion: Among 26 cases included in this review, ITP, CD, and comorbid ITP and CD were initially diagnosed in 8, 10, and 8 cases, respectively. The onset of ITP might be associated with CD aggravation in some cases. Although standard therapies in comorbid ITP and CD cases were glucocorticoids, intravenous immunoglobulin, biologics, and splenectomy, bowel resection for CD might achieve ITP remission in some cases. No fatalities were reported among 26 cases.

Author(s) Details:

Toru Shizuma,
Department of Physiology, Tokai University School of Medicine, 143, Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

Please see the link here: https://stm.bookpi.org/ANUMS-V8/article/view/13523

Concomitant Cases of Primary Biliary Cholangitis and Immune Thrombocytopenia | Chapter 6 | Advanced Concepts in Medicine and Medical Research Vol. 3

 Background: Although autoimmune afflictions are often accompanying, the place of primary biliary cholangitis (PBC) and invulnerable thrombocytopenia (ITP) is rare.Aim of Study: In this study, cases accompanying concomitant PBC and ITP, containing cases of Evans disease, were reviewed.Methods: A composition search on scientific items in English was conducted utilizing the PubMed table, regarding the place of PBC and ITP.Results and Conclusion: Among the 20 cases, PBC was diagnosed first in 6 cases and ITP in 2 cases, while two together diseases were nearly together diagnosed in the surplus 12 cases. Standard pharmacotherapies of ursodeoxycholic acid and corticosteroids were used for contributing cases. Of these cases, fatality was stated in 1 case.

Author(s) Details:

Toru Shizuma,
Department of Physiology, Tokai University School of Medicine, 143, Shimokasuya, Isehara, Kanagawa 259-1193, Japan.

Please see the link here: https://stm.bookpi.org/ACMMR-V3/article/view/12368