Friday, 22 March 2024

Exploring Ocular Morphological Alterations in Iron Deficiency Anemia through Optical Coherence Tomography: A Comprehensive Analysis | Chapter 7 | Advanced Research in Biological Science Vol. 9

Anemia, characterized by insufficient red blood cells and impaired oxygen-carrying capacity, affects billions globally, with a high prevalence among women and children. This study explores the multifactorial etiology of anemia, focusing on preventable factors such as inadequate diet, poor living conditions, and infections. Optical Coherence Tomography (OCT), a diagnostic tool offering high-resolution cross-sectional imaging of biological tissues, is employed to investigate the ocular impact of iron deficiency anemia (IDA). Various studies utilizing OCT reveal consistent correlations between IDA and structural changes in the peripapillary retinal fiber layer (RNFL) and macula. These changes are associated with serum ferritin levels, hemoglobin concentrations, and other iron profile parameters. In conclusion, this comprehensive review and study underscore the significance of OCT in evaluating ocular changes associated with iron deficiency anemia. The consistent patterns observed across multiple studies emphasize the potential clinical utility of OCT as a non-invasive tool for monitoring and managing IDA-related ocular manifestations. This research lays the foundation for further exploring and applying OCT in clinical assessments, offering valuable insights for early detection and intervention in preserving ocular health in anemic populations.


Author(s) Details:

Praveen Prashant,
Department of Biochemistry, Pt. B D Sharma PGIMS Rohtak, HR, India.

Dinesh Kumar,
Department of Physiology, World College of Medical Sciences, Jhajjar, Haryana, India.

Abhishek Bansal,
Department of Biochemistry, Pt. B D Sharma PGIMS Rohtak, HR, India.

Pragya Dixit,
ESI Health Care Haryana, ESI Hospital Panipat, HR, India.

Please see the link here: https://stm.bookpi.org/ARBS-V9/article/view/13734

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