The present study deal with the importance of the prognostic
factors of pneumonias (severity indices) as well as the fundamental issues of
the pathomechanism of sepsis. The characteristic of severe sepsis is multiorgan
dysfunction associated with sepsis due to the microcirculation disfunction of
the individual organs, accompanied with clinical signs of decreased
consciousness, oliguria, icterus, lactate acidosis, thrombocytopenia and
laboratory differences. During sepsis fundamental changes go on in the balance
situation of the procoagulant-anticoagulant system of the organism. Due to the
expression of the tissue factor the coagulation “cascade” system is activated
in the damaged and activated endothelium, and as a result, disseminated
arterial thromboses develop, and the interaction between fibrine and the
thrombocytes results in the development of microvascular thromboses.
Author(s) Details:
Geza Bozoky,
Hospital of Bács-Kiskun County Municipality, Hungary.
Eva
Ruby,
Department
of Pulmonology, Kecskemet, Hungary.
Please see the link here: https://stm.bookpi.org/RUDHR-V4/article/view/13820
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