Millions of people around the world undergo orthodontic
treatment to treat craniofacial disorders, correct their bites, and ultimately
achieve a beautiful smile. However, orthodontic treatment has many significant
challenges that require a better understanding of the molecular-biochemical
mechanisms involved in orthodontic tooth movement. Orthodontic treatment is a
multifactorial process, occurring with the participation of many signaling
molecules and the involvement of different metabolic pathways. Orthodontic
treatment is the finely regulated, continuous process of bone remodeling, which
occurs through the highly coordinated interaction of different types of bone
cells: osteoblasts, which participate in bone formation, and osteoclasts, which
destroy bone. The true picture of the processes mentioned remains to be
investigated, but more and more information suggests the possible role of
individual neurochemical players in the above-mentioned processes.
This review aims to summarize the available data regarding
the various neurochemical regulators and receptor systems involved in
orthodontic treatment processes.
Author(s) Details:
Eleonora R. Ghazaryan,
Department of Pediatric Dentistry and Orthodontics, Yerevan State
Medical University, Armenia.
Gayane
S. Vardanyan,
Department
of Biochemistry, Yerevan State Medical University, Armenia.
Michail I. Aghajanov,
Department of Biochemistry, Yerevan State Medical University,
Armenia.
Hrant Y. Ter-Poghosyan,
Department of Pediatric Dentistry and Orthodontics, Yerevan State
Medical University, Armenia.
Mikayel S. Nalbandyan,
Department
of Pediatric Dentistry and Orthodontics, Yerevan State Medical University,
Armenia.
Please see the link here: https://stm.bookpi.org/RUDHR-V3/article/view/13709
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