Eclipta alba is the traditional medicine widely used for the
treatment of gastrointestinal disorders, respiratory tract disorders (including
asthma), fever, hair loss and graying of hair, liver disorders (including
jaundice), skin disorders, spleen enlargement, and cuts and wounds. It is also
proven as an effective anticancer, hepatoprotective, snake venom neutralizing,
anti-inflammatory, and antimicrobial drug. The main phytoconstituents like
wedelolactone, ecliptalbine luteolin, ursolic acid, oleanolic acids and
apigenin has formed a basis of new drugs against cancer, arthritis,
gastrointestinal disorders, skin diseases, and liver disorders. The present
study was carried out to investigate the anthelmintic potential of methanolic
extract of the whole plant of Eclipta alba (L.) Hassk against Pheretima
posthuma as a species of earthworm. Various concentrations (25-100 mg/ml) of
methanolic extract were evaluated for anthelmintic activity by recording the
time required for paralysis and death of worms. Albendazole was used as
standard. The result indicates that methanol extracts significantly (p<0.01)
exhibited paralysis at lower doses of 50, 75 and 100 mg/ml and caused death of
worms at doses of concentrations 75 and 100 mg/ml when compared with standard.
Author(s) Details
Sujata R. Khatal
Amrutvahini Institute of Pharmacy, Sangamner, MH, India.
Machindra J. Chavan
Amrutvahini College of Pharmacy, Sangamner, MH, India.
Dipak N. Raut
Amrutvahini College of Pharmacy, Sangamner, MH, India.
Please see the book here:- https://doi.org/10.9734/bpi/prrat/v4/1300
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