Despite significant advancements in wound therapy, the
pursuit of innovative wound dressing materials remains fervent. This study aims
to analyze the physiochemical characteristics and biological performance of a
novel wound dressing material. The material was synthesized using
Physiologically Clotted Fibrin (PCF) and Fish Scale Collagen (FSC), bolstered
by the medicinal properties of Spider Web (SW) and Ethanolic Extract of
Mangifera indica (L.) (EEMI). Infrared spectroscopic analysis confirmed the
presence of Type I collagen, while surface morphology revealed a smooth,
uniform, and porous structure, demonstrating biocompatibility. Water absorption
and porosity measurements met required standards, while antibacterial assays
revealed its combat against different bacteria. Additionally, ash tests
underscored its eco-friendly nature. Biocompatibility assessments with human
erythrocytes showed favourable results. Haemolysis assays at various
concentrations and incubation times demonstrated the material's non-haemolytic
behaviour. O all, the synthesized biomaterial presents as a promising wound
dressing option, boasting efficacy, cost-effectiveness, and environmental
sustainability.
Author(s) Details
Subbukutti Veerabahu
PG Department of Physics, Bhaktavatsalam Memorial College
for Women, Chennai- 600 050, India.
Umadevi Kumba
Janarthanan
PG & Research Department of Biochemistry, Bhaktavatsalam
Memorial College for Women, Chennai-600 050, India.
Please see the link:- https://doi.org/10.9734/bpi/crpps/v2/581
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