Background: Nardostachys jatamansi DC, commonly known as Indian spikenard, has a rich historical significance rooted in ancient texts. This widely utilised herb in traditional Chinese medicine has been historically employed in the management of various neuropsychiatric disorders.
Objectives: This review aims to consolidate existing knowledge on
Nardostachys jatamansi (Indian spikenard), exploring its historical
significance, botanical characteristics, chemical composition, and
pharmacological activities to provide a comprehensive resource for researchers
and clinicians.
Methodology: Information was gathered from Ayurvedic texts, modern
scientific literature, and electronic databases including Google Scholar,
ScienceDirect, Springer, and PubMed. The search included articles published up
to 2025, using keywords such as "Nardostachys jatamansi,"
"botany of Nardostachys jatamansi," and "pharmacological
activity of Nardostachys jatamansi." A systematic review of selected
literature was conducted, focusing on botanical classification, taxonomy, ethnobotany,
phytochemistry, and pharmacology. Data were analysed to identify traditional
uses, chemical constituents, and experimentally validated pharmacological
effects.
Results: Nardostachys jatamansi is highly regarded in Ayurvedic
medicine for its diverse therapeutic properties, classified under various
actions that promote health and well-being. Nardostachys jatamansi contains
diverse chemical constituents, including terpenes, fatty acids, and other
compounds such as jatamansone and nardostachone. Traditional uses in Ayurveda
include treatments for neurological, cardiovascular, and dermatological
conditions. Modern pharmacological studies support its antifungal,
antibacterial, hepatoprotective, cardioprotective, hypolipidemic,
antidepressant, antioxidant, neuroprotective, antiparkinson, anticonvulsant,
anti-hyperglycemic, and anticancer activities.
Conclusion: Nardostachys jatamansi is a herb with significant
therapeutic potential, supported by both traditional use and modern scientific
evidence. Its diverse pharmacological activities warrant further investigation
to explore clinical applications and develop novel therapeutic agents.
Author(s)
Details
Shubham
Kamble
Department of Pharmaceutics, The Royal Gondwana College of
Pharmacy, Nagpur, India.
Bhagyashri
R. Dhakate
Department of Pharmaceutics, National College of Pharmacy, Nagpur,
India.
Kunjan
Faye
Department of Pharmaceutical Chemistry, Institute of Diploma in
Pharmacy (Govt. Aided), Borgaon (Meghe), Wardha, India.
Harsha
P. Sontakke
Department of Pharmaceutical Chemistry, National College of
Pharmacy, Nagpur, India.
Janhavi
Indurkar
Department of Pharmaceutical Chemistry, Central India College of
Pharmacy, Nagpur, India.
Meenal
Watkar
Department of Pharmaceutical Quality Assurance, Central India
College of Pharmacy, Nagpur, India.
Please see the book here:- https://doi.org/10.9734/bpi/psnid/v7/5882
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