Prominent Use of Malva sylvestris L in Dermatology | Chapter 8 | Research Perspective on Biological Science Vol. 9

 

Malva sylvestris L. (common mallow) is a flowering plant belonging to the Malvaceae family. The plant has laxative, diuretic, spasmogenic and laxative properties. This plant has a rich history in traditional medicine across Asia, Europe, and Africa, and presents a compelling natural therapeutic agent for a wide range of dermatological conditions. Among the various species used in herbal medicine, M. sylvestris stands out for its diverse usage, which has been documented since 3000 BC. In Iran, M. sylvestris is recognised as an edible herb and has been consumed raw in various vegetable salads; however, it is most commonly used as a medicinal herb. This review consolidates scientific evidence to validate its traditional use in treating wounds, eczema, atopic dermatitis, and skin infections. The therapeutic efficacy of M. sylvestris is primarily attributed to its diverse profile of bioactive phytoconstituents. Key among these are mucilaginous polysaccharides, which provide emollient and soothing effects for sensitive skin and irritations; flavonoids (e.g., gossypetin, malvidin 3-glucoside) and phenolic compounds, which exert potent antioxidant and anti-inflammatory activities by scavenging free radicals and modulating inflammatory mediators like PGE₂; and tannins and essential oils, which contribute to its significant antibacterial effects against pathogens such as Staphylococcus aureus. Preclinical and clinical studies demonstrate that topical applications of M. sylvestris extracts promote wound healing by enhancing collagen deposition and fibroblast proliferation, reduce inflammation and pruritus in atopic dermatitis, and accelerate burn wound contraction, often showing superior efficacy compared to standard treatments like silver sulfadiazine. The convergence of its demulcent, antibacterial, anti-inflammatory, and antioxidant properties, underpinned by its distinct phytochemical composition, justifies its traditional use and positions M. sylvestris as a versatile and effective candidate for integrative dermatological therapy. Future studies, including well-designed clinical trials and standardised extract formulations, are required to validate the therapeutic efficacy of Malva sylvestris in dermatological conditions.

 

 

Author(s) Details

Farshad Akbarnejad
Scientific Department, Rayka Shimi Saba Pharmaceutical & Hygienic Knowledge-Based Co., Tehran, Iran.

 

Please see the link:- https://doi.org/10.9734/bpi/rpbs/v9/6800

 

Therapeutic and Pharmacological Insights into Nardostachys jatamansi DC: Bridging Traditional Use and Modern Science | Chapter 7 | Pharmaceutical Science: New Insights and Developments Vol. 7

Background: Nardostachys jatamansi DC, commonly known as Indian spikenard, has a rich historical significance rooted in ancient texts. This widely utilised herb in traditional Chinese medicine has been historically employed in the management of various neuropsychiatric disorders.

 

Objectives: This review aims to consolidate existing knowledge on Nardostachys jatamansi (Indian spikenard), exploring its historical significance, botanical characteristics, chemical composition, and pharmacological activities to provide a comprehensive resource for researchers and clinicians.

 

Methodology: Information was gathered from Ayurvedic texts, modern scientific literature, and electronic databases including Google Scholar, ScienceDirect, Springer, and PubMed. The search included articles published up to 2025, using keywords such as "Nardostachys jatamansi," "botany of Nardostachys jatamansi," and "pharmacological activity of Nardostachys jatamansi." A systematic review of selected literature was conducted, focusing on botanical classification, taxonomy, ethnobotany, phytochemistry, and pharmacology. Data were analysed to identify traditional uses, chemical constituents, and experimentally validated pharmacological effects.

 

Results: Nardostachys jatamansi is highly regarded in Ayurvedic medicine for its diverse therapeutic properties, classified under various actions that promote health and well-being. Nardostachys jatamansi contains diverse chemical constituents, including terpenes, fatty acids, and other compounds such as jatamansone and nardostachone. Traditional uses in Ayurveda include treatments for neurological, cardiovascular, and dermatological conditions. Modern pharmacological studies support its antifungal, antibacterial, hepatoprotective, cardioprotective, hypolipidemic, antidepressant, antioxidant, neuroprotective, antiparkinson, anticonvulsant, anti-hyperglycemic, and anticancer activities.

 

Conclusion: Nardostachys jatamansi is a herb with significant therapeutic potential, supported by both traditional use and modern scientific evidence. Its diverse pharmacological activities warrant further investigation to explore clinical applications and develop novel therapeutic agents.

 

Author(s) Details

Shubham Kamble
Department of Pharmaceutics, The Royal Gondwana College of Pharmacy, Nagpur, India.

 

Bhagyashri R. Dhakate
Department of Pharmaceutics, National College of Pharmacy, Nagpur, India.

 

Kunjan Faye
Department of Pharmaceutical Chemistry, Institute of Diploma in Pharmacy (Govt. Aided), Borgaon (Meghe), Wardha, India.

 

Harsha P. Sontakke
Department of Pharmaceutical Chemistry, National College of Pharmacy, Nagpur, India.

 

Janhavi Indurkar
Department of Pharmaceutical Chemistry, Central India College of Pharmacy, Nagpur, India.

 

Meenal Watkar
Department of Pharmaceutical Quality Assurance, Central India College of Pharmacy, Nagpur, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/psnid/v7/5882

Precis of the Phytochemical and Pharmacological Components of the Jungle Jalebi (Pithecellobium dulce) | Chapter 4 | Pharmaceutical Research: Recent Advances and Trends Vol. 5

 

The present review outlined the Phytochemical and Pharmacological Components of the Jungle Jalebi (Pithecellobium dulce). Pithecellobium dulce has numerous utilisations which has flexible jobs in the conventional arrangement of medication. The chemical compounds present in plants are used as antidiabetics, anticancer, anti-inflammation, etc. There are several allopathic medicines used in the treatment of diseases but they also have several side effects and drug interactions, so there is a need for herbal treatments that have lesser or no side effect. A few investigations are being directed concerning the viability of the entire plant or its parts for the treatment of various sicknesses and ailments. Triterpenoids, sterols, flavonoids, tannins, and phytocompounds like quercetin, kaempferol, and dulcitol were recognized from the different pieces of the plant. In this article, the different remedial properties of P. dulce have been shown. P. dulce is an evergreen sharp tree; each piece of the plant has huge healthful values. The pharmacological activities of various plant parts, such as their anti-diabetic, locomotor, immunizing agent venom, protease inhibitor, free radical searching, mitigating, anti-bacterial, anti-mycobacterial, abortifacient, spermicidal, anti-convulsant, anti-ulcer, anti-diarrheal, anti-tubercular, anti-tumour, and anti-oxidative properties, have been demonstrated. Safety studies, such as acute and sub-acute toxicity studies, have also demonstrated various pharmacological activities of plants. More examinations are required to investigate the utilisation of the plant for the commercialization of dynamic elements of organic and home-grown medication applications.

 

Author(s) Details

 

Abdul Hameed
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.

 

Yash Srivastav
Azad Institute of Pharmacy & Research, Lucknow, U.P, India.

 

Alka Verma
RGS College of Pharmacy, Lucknow, U.P, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/prrat/v5/1599

Capparis decidua Edgew (Forssk.): An Across-the-board Review of Its Traditional Uses, Pharmacology of Anti-cancer Potential | Chapter 1 | Novel Aspects on Pharmaceutical Research Vol. 2

 Chemoprevention is a new approach that employs natural plant and herbal products to prevent, delay, or even halt the progression of cancer, which is the second most common cause of death after cardiovascular disease and a major cause of mortality in affluent nations. In the pursuit of anti-neoplastic effects, traditional plant remedies are often combined with synthetic drugs. Capparis decidua, a plant species, has been found to possess several pharmacological properties, including anti-diabetic, anthelmintic, antibacterial, antifungal, analgesic, anti-nociceptive, anti-rheumatic, hypo-lipidemic, anti-tumor, anti-giardial, antioxidant, anti-inflammatory, hepato-protective, and anticonvulsant effects, among others. The caper plant's incredible bioactivity is attributed to its various phytochemicals, such as alkaloids (capparisinine, capparisine, stachydrine, and iso-codonocarpine), phenolics, flavonoids, sterols, and fatty acids. This section covers the traditional applications, phytochemistry, and pharmacology of Capparis decidua, which has tremendous potential with various mechanisms to address the research gap for future researchers.

Author(s) Details:

Rajshree Dahiya,
jai Narain Vyas University, Jodhpur, India.

Please see the link here: https://stm.bookpi.org/NAPR-V2/article/view/10594

Ethnobotanical Uses of Some Common Plants in Uttarakhand, India: A Review | Chapter 9 | Challenges and Advances in Pharmaceutical Research Vol. 7

 Due to varying climate and topography there s a wide range of vegetation which serve as habitats to diverse species of wild life. Due to the richness in variety of vegetation the forest occupies a place of pride in the environment. The present study focuses on the Ethnobotanical uses of some common plants of Matli village, Uttarkashi district. 15 tree species belonging to 14 families common in the area have been reported. All the plants reported from the area have medicinal importance. The details of the plants such as botanical name, family, parts used, uses, common name, plant parts most harvested and the use of different parts for different medicinal purpose etc are also given in the paper. Future conservation efforts should pay particular attention to the value of medicinal plants and incorporate measures to ensure their preservation and long-term viability. Additional research is needed to fully understand several features of these plants, including their photochemical, biochemical, antibacterial, antifungal, and antihelminthic properties.

Author(s) Details:

Chhaya Singh,
Shri Guru Ram Rai University, Patel Nagar, Dehradun, India.

Priyanka Nautiyal,
Shri Guru Ram Rai University, Patel Nagar, Dehradun, India.

Neha Chauhan,
Shri Guru Ram Rai University, Patel Nagar, Dehradun, India.

Shagun Gupta,
Shri Guru Ram Rai University, Patel Nagar, Dehradun, India.

Please see the link here: https://stm.bookpi.org/CAPR-V7/article/view/8372

The Potency and Efficacy of Essential Oils from Selected Aromatic Crop Species Commercially Grown in Uganda: A Review of their Use in Animal and Human Therapeutics | Chapter 15 | Challenges and Advances in Pharmaceutical Research Vol. 4

Due to the synthesis of active chemicals, there is a growing usage of essential oils from aromatic crops in the beverage, pharmaceutical, apiary, and cosmetics sectors in addition to aromatherapy. It has been demonstrated that essential oils contain bactericidal, virucidal, fungal, anti-parasitic, and insecticidal properties. The objective of this review was to present a summary of the effectiveness and potency of chosen aromatic crop species that are commercially cultivated in Uganda. With potency, traditional medicinal uses, pharmacological or biological activity, toxicity, phytochemistry, and efficacy of Cymbopogon citratus, Salvia rosmarinus, Eucalyptus citriodora, and Lavandula anguistifolia as the key search terms, we reviewed pertinent articles, books, theses, dissertations, patents, and other English-only reports. Between June and November 2021, we searched databases including PubMed, Web of Science, Scopus, and Science Direct as well as search engines like Google Scholar. The essential oils were said to have antioxidant, insecticidal, insecticidal, larvicidal, anticancer, anthelmintic, and insecticidal properties. Additionally, rosemary oil stimulated the neurological system, prevented the growth and release of aflatoxin, and kept mayonnaise stable during storage. The biological effects that essential oils demonstrated in this research support their present and potential usage in the food, cosmetic, and pharmaceutical sectors.

Author (s) Details:

Patience Tugume,
Department of Plant Sciences, Microbiology & Biotechnology, Makerere University, P.O.Box 7062, Kampala, Uganda.

Maud Kamatenesi-Mugisha,
Ethnobiology Laboratory, Bishop Stuart University, P.O.Box 09, Mbarara, Uganda.

George Byarugaba Bazirake,
Department of Food Technology, Faculty of Science, Kyambogo University, P.O.Box 1, Kampala, Uganda.

Waisindye Noah,
Ethnobiology Laboratory, Bishop Stuart University, P.O.Box 09, Mbarara, Uganda.

Savina Asiimwe,
Department of Plant Sciences, Microbiology & Biotechnology, Makerere University, P.O.Box 7062, Kampala, Uganda.

Please see the link here: https://stm.bookpi.org/CAPR-V4/article/view/7524

Kanakchampa | Chapter 11 | Current Aspects in Pharmaceutical Research and Development Vol. 3

 The herb Pterospermum acerifolium (Sterculiaceae) is found all over the world. This plant is also known by the names Kanakchampa, Karnikara, Muchukunda, and Matsakanda. It reaches a height of 60 feet. The plant's leaves are frequently used as a haemostatic and in Indian proprietary medications to treat diabetes. Antioxidant, antiulcer, anti-inflammatory, analgesic, hypoglycemic, immunosuppressive, wound healing, hepatoprotective, antihelmentic, antimitotic, and anticancer characteristics have been discovered in the plant. Inflammation, abdominal pain, ascites, ulcers, leprosy, constipation, urine discharges, and tumours are supposed to be treated with it. The first stage in assessing whether a plant organ is suitable for use as a crude medication is pharmacognosy. As a result, a comprehensive Pharmacognostic analysis of Pterospermum acerifolium (L.)Willd seed was carried out. The current study covered a wide range of pharmacognosy topics, including macroscopy, microscopy, histochemical analysis, powder study, preliminary phytochemical screening, fluorescence analysis, and physicochemical constants.

Author(S) Details

Neetu Deshwal
School of Pharmaceutical Sciences, CT University, Ludhiana, Punjab, India.

Saurabh Sharma
School of Pharmaceutical Sciences, CT University, Ludhiana, Punjab, India.

View Book:- https://stm.bookpi.org/CAPRD-V3/article/view/4446

Overview on Prosopis cineraria (L.) Druce: A State Tree of Rajasthan and Telangana | Chapter 13 | Recent Developments in Medicine and Medical Research Vol. 2

 Cineraria Prosopis (L.) Leguminosae, Druce family, Synonym Prosopis spicigera, also known as Khejri, Janti, and Sami, is a deep-rooted, nitrogen-fixing, multipurpose tree native to India's scorching deserts. It contributes to the region's ecological stability by giving significant support to humans, cattle, and nutrient-depleted soils. Rajasthan and Telangana each have it as their state tree. It is also the United Arab Emirates' national tree. 5-hydroxytryptamine, apigenin, isorhamnetin-3-diglucoside, l-arabinose, quercetin, tannin, and tryptamine have all been discovered in Prosopis. Patulitrin, a patuletin glucoside, has been isolated from the flowers. Fixed oils (4.5 percent) and fatty acids such as palmitic acid, stearic acid, oleic acid, and linoleic acid are found in seeds. It has traditionally been used to treat helminthiasis, leprosy, dysentery, bronchitis, asthma, leucoderma, piles, mental wandering, and muscle spasms. This article discusses the plant's phytochemical, pharmacological, traditional, and medicinal value.

Author (S) Details

Anirudh Khatri

Department of Pharmaceutical Sciences, Mohanlal Sukhadia University, Udaipur- 313001, Rajasthan, India.

Anita Rathore

Department of Veterinary Pathology, College of Veterinary and Animal Science, RAJUVAS, Navania, Vallabhnagar, Udaipur-313601, Rajasthan, India.

Chandra Prakash Jain

Department of Pharmaceutical Sciences, Mohanlal Sukhadia University, Udaipur- 313001, Rajasthan, India.

View Book :- https://stm.bookpi.org/RDMMR-V2/article/view/4284

 

Plants in Herbal Medicine; Their Traditional Uses, Chemistry and Biology | Book Publisher International

 The first textbook to cover the exciting multidisciplinary areas of herbal medicine, this valuable book is a must-have. The book focuses on the traditional applications of over 400 medicinal plants that grow in the West African sub-region and other areas with similar climatic conditions. It also discusses secondary metabolic products, emphasising the existence of alkaloids, flavonoids, vitamins, terpenes and terpenoids, quinones, lignans and their derivatives, proteins, carbohydrate molecules, and so on. The book goes on to discuss the unintended consequences of plant extracts or isolated chemical components acting on laboratory animals, as well as the human body and animals in some circumstances. Some of the results of previous research have been highlighted, including those affecting the cardiovascular system, respiratory system, and nervous system, as well as those with anticancer, antimicrobial, anti-allergenic, antioxidant, parasiticidal, immuno-stimulatory, anti-inflammatory, and family planning properties, as well as those used for prostate and urinary problems in humans and animals.

Author(S) Details

Simeon Kolawole Adesina
(Retd. Professor), Drug Research & Production Unit, Faculty of Pharmacy, Obafemi Awolowo University, Ile-Ife, State of Osun, Nigeria.

Imoh Imeh Johnny
Department of Pharmacognosy & Natural Medicine, Faculty of Pharmacy, University of Uyo, Uyo, Akwa Ibom State, Nigeria.

View Book:- https://stm.bookpi.org/PHMTTUCB/article/view/3233

Investigation of Bioactive Compounds and Antioxidant Activity of Excoecaria agallocha L.: Critical Overview | Chapter 12 |New Perspectives in Agriculture and Crop Science Vol. 2

Mangrove survives in the most hostile environment with fluctuating tidal and saline regime. The present work focused on a detailed study on quantitative estimation of phytoconstituents and DPPH radical scavenging activity of Excoecaria agallocha L., a mangrove from Kattiparambu and Chirackal of Ernakulam District, Kerala. Preliminary phytochemical investigation indicated the presence of biologically active metabolites of leaf, stem and root of the plant in different solvents. Methanol and hexane gave maximum results. Since the plant grows in stress conditions showed the presence of amino acids. Recorded values for high protein in leaf (4.8%), stem (1.93%), Carbohydrate in the root (11.17%) at Chirackal. Phenols (6.02%), flavanoids (3.6%) and tannins (5.68%) was observed in leaf samples of the species at Chirackal. Methanolic extract showed maximum free radical scavenging activity (IC50-141.56 µg/ml) in leaf samples and stem showed minimum (IC50-931.3 µg/ml) in chloroform extract. The range of DPPH radical scavenging activity in the solvent is Methanol > Ethyl acetate > Ethanol > Chloroform. 

Author(s) Details 

S. Sofia
Department of Botany, St. Teresa’s College, Ernakulam, Kerala, India. 

View Book: - http://bp.bookpi.org/index.php/bpi/catalog/book/172