This case report highlights a challenging clinical case
called glycogen hepatopaty-induced acute hepatitis. This clinical condition is
often underdiagnosed or misdiagnosed even by consultant specialists eventually
hampering patient management and outcome. Glycogen hepatopathy is a very rare
and forgotten complication of poorly controlled type 1 diabetes mellitus.
Glycogen hepatopathy may also present in type II diabetes mellitus, especially
when managed with high doses of insulin. Although it is a benign condition, it
is rarely diagnosed in a timely manner. It is characterised by hepatomegaly
causing abdominal pain due to stretch on the liver capsule causing capsulitis,
and derangement of liver enzymes. We report a case of a 44-year-old male truck
driver who presents to ED with right upper quadrant pain in the context of
uncontrolled type II diabetes mellitus for the last two years. Glycogen hepatopathy is caused by wide
fluctuations of blood glucose and treatment with large doses of insulin. High
levels of insulin due to uncontrolled diabetes mellitus or high doses for
treatment lead to excess glucose movement into hepatocytes via independent
passive diffusion.
Author (s) Details
Adel Ekladious
Acute Medical Unit, Canberra Hospital, ACT Health, Australia, University of
Western Australia, Australia and Australian National University, Australia.
Please see the book:- https://doi.org/10.9734/bpi/rudhr/v9/241
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