The Effects of General Anaesthetics in Immune Modulation and Cancer Outcome | Chapter 4 | Innovations in Biological Science Vol. 3

Patients with oncologic disease require the use of anaesthetic agents at some point in their treatment. However, during the perioperative period, anaesthetic agents, surgical tissue trauma, adjuvant therapies for local pain and inflammation, and other non-pharmacological elements, such as corporal and hydration conditions and blood transfusions, can have an impact on the disease's outcome, which has a significant influence on the immune response of an oncologic patient. The immune response capacity is the principal barrier to tumour progression, creating a window of susceptibility for tumour dissemination or recurrence. Further investigation is warranted to ascertain the immunoprotective and anti-tumour properties of various anaesthetics and procedures, thereby facilitating the advancement of novel veterinary anaesthetic methodologies.

Author(s) Details:

Ana Vidal Pinheiro,
Department of Veterinary Sciences, School of Agricultural and Veterinary Sciences (ECAV), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal and CECAV—Veterinary and Animal Research Center, University of Trás-os-Montes and Alto Douro, 5001-801 Vila Real, Portugal.

Gonçalo N. Petrucci,
Onevetgroup Hospital Veterinário do Porto (HVP), 4250-475 Porto, Portugal, Center for Investigation Vasco da Gama (CIVG), Department of Veterinary Sciences, Vasco da Gama University School (EUVG), 3020-210 Coimbra, Portugal and CECAV—Veterinary and Animal Research Center, University of Trás-os-Montes and Alto Douro, 5001-801 Vila Real, Portugal.

Amândio Dourado,
Department of Veterinary Sciences, School of Agricultural and Veterinary Sciences (ECAV), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal and Onevetgroup Hospital Veterinário do Porto (HVP), 4250-475 Porto, Portugal.

Isabel Pires,
Department of Veterinary Sciences, School of Agricultural and Veterinary Sciences (ECAV), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal and CECAV—Veterinary and Animal Research Center, University of Trás-os-Montes and Alto Douro, 5001-801 Vila Real, Portugal.

Please see the link here: https://stm.bookpi.org/IBS-V3/article/view/14243