Root canal therapy or apexification is the standard
treatment for teeth that are irreversibly diseased or necrotic. By attempting
to repair the injured "pulp-like" tissue, regenerative endodontics
can prevent necrosis and maintain the vitality of the teeth. The main clinical benefit is the development
of root. The term "pulp-like" tissue does not relate to pulp-dentin
complex development or regenerated pulp tissue with an odontoblastic layer.
The ability of endogenous stem cells to regenerate tissue is the foundation of
the cell homing technology. The term "cell homing" describes the
migration or infiltration of endogenous cells into the cite in response to
physiological, biochemical, or biological stimuli, or through passive flow in
the form of a blood clot from the apical tissue. The American Association of
Endodontists has established its success criteria for Regenerative Endodontic
Procedures. Despite difficulties, Heet al. (2017) found that cell homing is now
the most clinically viable method for dental pulp regeneration. Future advancements
in tissue engineering could lead to new scaffold designs, antibacterial
protocols, and the use of other signalling molecules, improving the outcome's
predictability. This review study aims to provide a summary of cell homing as
well as a number of strategies for encouraging the regeneration of damaged
pulp.
Author(s) Details:
R Sumukh Bharadwaj,
Department of Conservative Dentistry & Endodontics, JSS Dental
College & Hospital, Mysuru, India.
Ashwini
Tumkur Shivakumar,
Department of Conservative Dentistry &
Endodontics, JSS Dental College & Hospital, Mysuru, India.
Sowmya
Halasabalu Kalgeri,
Department of Conservative Dentistry &
Endodontics, JSS Dental College & Hospital, Mysuru, India.
Adarsh
Choudhary,
Department of Oral & Maxillofacial Surgery, JSS
Dental College & Hospital, Mysuru, India.
Prajwal M S,
Department
of Oral & Maxillofacial Surgery, JSS Dental College & Hospital, Mysuru,
India.
Supreeth S Gowda,
Department of Conservative Dentistry & Endodontics, JSS Dental College
& Hospital, Mysuru, India.
Please see the link here: https://stm.bookpi.org/CHTNATRE/article/view/13557
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