A Review on the Ameliorative Effects of Sheep Milk Bioactives on Mental Health through the Gut–brain Axis |Chapter 9 | Research Perspective on Biological Science Vol. 8

 

Probiotics improve gut health and also enhance mental states, such as mood and reduce stress. The properties of Caprine milk have facilitated their application as an alternative source of probiotics. Two decades of research have implicated that human microbiota have far-reaching consequences in the mental health and well-being through the gut-brain axis (GBA-axis). With the increase in the probiotics consumption and demand for alternative sources of probiotics, it is imperative to review the current knowledge and trends in the area. In the initial section, we provide background knowledge on probiotics and gut microbiome, neuronal pathways involved in the GBA axis. The Gut and mental disorders, along with clinical studies, are covered to provide deeper insights into the therapeutic aspects of probiotics. The cellular and ameliorative properties of sheep milk bioactive molecules in CNS functions in covered in detail to correlate the roles of the bioactive molecules in CNS functions. The data will help unravel the gut-brain axis and pave the way for a better understanding of the mechanisms and alterations. This is an essential step in designing better prebiotics for mental health. As the global burden of mental disorders continues to mount, with a large population of elderly subjects supplemented probiotics which promote mental health and well-being in the need of the hour. The review thus by covers overlapping areas of food, gut, and neuroscience brings filling prevailing knowledge gaps in the field and providing scopes for future research.

 

 

Author(s) Details

Rajesha S
Department of Zoology and Genetics, Government Science College, Nrupathunga University, Nrupathunga Road, Bangalore, 560001, India.

 

Ravikumar Patil H S
Department of Studies in Food Technology, Shivagangotri, Davangere University, Davanagere, India.

 

Prabhu Rajeshwar
Department of Studies in Biotechnology, Shivagangotri, Davangere University, Davanagere, India.

 

Kiran Kumar H.B
Nrupathunga University, India.

 

Kumara B.P.
Department of Studies in Biotechnology, Shivagangotri, Davangere University, Davanagere, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/rpbs/v8/6577