The present study investigates the effect of Averrhoa
carambola ethanolic fruit extract on gonadal function and structure in female
Wistar rats. Plant products with higher medicinal properties have been
connected to a substantial impact on the development of novel medications.
Averrhoa carambola is a well-known medicinal plant with significant antioxidant
properties that is frequently used as a reproductive plant by herbalists
without scientific support. A total of 15 Wistar rats weighing 100 to 143g were
divided into three groups of five rats each. Food and distilled water were
given to Group A, 500 mg/kg of ethanolic fruit extract of A. carambola was
given to Group B, and 1000 mg/kg of ethanolic fruit extract of A. carambola was
given to Group C every day for 21 days there was a substantial rise in ovarian
and uterine weight in groups B and C after receiving the Averrhoa carambola
fruit extract when compared to the control group. However, when compared to the
control group, LH increased (p>0.0) while progesterone declined
significantly. According to the findings, the extract's structural effects on
the gonads of female rats were shown to be adverse. In conclusion, Averrhoa
carambola fruit extract may be more beneficial as a contraceptive than a
pro-fertility agent, as traditional medicine practitioners claim. The finding
of this study showed that Averrhoa carambola fruit extract may have a
beneficial effect on body weight, relative ovary and uterine weight, and FSH
and LH activities.
Author(s) Details:
Ifedi I. Charles,
Department of Human Physiology, Faculty of Basic Medical Sciences,
College of Medicine, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria.
Emeka Ugwuishi
Department of Human Physiology, Faculty of Basic Medical Sciences, Enugu
State University College of Medicine, Parklane, Nigeria.
Ifedi O. Blessing
Department of Human Physiology, Faculty of Basic Medical Sciences, College
of Medicine, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria.
Nwafor C. Charles
Department of Human Physiology, Faculty of Basic Medical Sciences, Enugu
State University College of Medicine, Parklane, Nigeria.
Okeke C. Jennifer
Department of Human Physiology, Faculty of Basic Medical Sciences, College of
Medicine, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria.
Okoye O. Fidelis
Department of Human Physiology, Faculty of Basic Medical Sciences, College of
Medicine, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria.
Ihezuruoha S. Chinyere
Department of Human Physiology, Faculty of Basic Medical Sciences, College of
Medicine, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria.
Please see the link here: https://doi.org/10.9734/bpi/nvmms/v8/3684G
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