Using disc diffusion (DD) and agar well diffusion (AWD) protocols, the antibacterial ability of crude turmeric rhizome extracts in combination with Potassium aluminium sulphate (PAS / Alum) against four (4) bacterial species was calculated. All the test bacteria were sensitive to dose-dependent extracts with and without PAS. DD 's highest inhibition zone diameter (DIZ) was observed with ethanolic turmeric extract (ETE) in combination with PAS (ETE+PAS) at a concentration of 0.3 g on Escherichia coli (16.6±0.8 mm) and Pseudomonas fluorescens (15.3±1.1 mm) and Staphylococcus aureus (15.0±0.0 mm). PAS had the strongest operation with AWD at a concentration of 0.3 g on Bacillus cereus (17.8±1.0 mm), S. On P. fluorescens and E. aureus (16.0 ±0.7 mm) and 14.0 mm Respectively, coli. In addition, antibacterial enhancement Wide spectrum activity is indicative of activity against both Gram positive and Gram negative bacteria with extracts of turmeric with PAS. However, on the other hand, the sensitivity of the test bacteria to the treatment strategy of turmeric extracts and PAS to Ofloxacin was less successful. This highlights the preference for the use of synthetic drugs for infection control, but natural substances are favoured alternatives because they have nutraceutical, medicinal and fewer side effects due to increased antimicrobial drug resistance (AMR) and apparent side effects.
Author(s) Details
Lawrence O. Amadi
Department of Microbiology, Faculty of Science, Rivers State University, P.M.B. 5080, Nkpolu-Oroworukwo, Port Harcourt, Nigeria and Department of Microbiology, School of Applied Science, Ken Saro-Wiwa Polytechnic, P.M.B. 20, Bori, Rivers State, Nigeria.
Joy S. Ekechi
Department of Microbiology, Faculty of Science, Rivers State University, P.M.B. 5080, Nkpolu-Oroworukwo, Port Harcourt, Nigeria.
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