Mitochondria-Targeted Therapies for Neurodegenerative Diseases | Chapter 9 | An Overview of Disease and Health Research Vol. 1

 Many neurodegenerative illnesses, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are characterised by mitochondriadysfunction. Neuronal degeneration is a result of alteration of mitochondrial dynamics, elevated oxidative stress, and impaired mitochondrial bioenergetics. One intriguing treatment approach to slow the progression of disease is to target the mitochondria. Recent developments in mitochondria-targeted medicine delivery, such as gene therapy, nanoparticles, small compounds, and mitochondrial transplantation techniques, are examined in this chapter. It also draws attention to the difficulties and potential uses of these tactics in healthcare settings.

 

Author (s) Details

Venkatalakshmi Ranganathan
Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science & Technology, Chennai-600048, India.

 

Preethi. M
Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science & Technology, Chennai-600048, India.

 

Roshni. N
Department of Pharmaceutics, Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science & Technology, Chennai-600048, India.

 

Sasikala Chinnappan
Department of Pharmaceutical Biology, UCSI University, Taman Connaught, 56000 Cheras, Malaysia.

 

Please see the book here:- https://doi.org/10.9734/bpi/aodhr/v1/5396