Background: The coronavirus disease (COVID-19) posed one of the deadliest pandemics since the outbreak of the Spanish flu. The already COVID-19 pandemic burdened nations, during epidemics have to cope up with dengue fever too. The continuous circulation of both viruses presented a significant problem for the healthcare system, which struggles with patient triage and prognosis. It’s suggested that dengue antibodies cross react with SARS-CoV-2. The coincident incidence of COVID-19 and dengue makes timely patient diagnosis, treatment and disease prevention difficult. However, it’s unknown whether patients with previous COVID 19 infection can develop immunity dengue virus.
Aim: To study the hematological
parameters in patients with active dengue infection and its correlation with
past history of COVID 19 infection. Secondary aim: To investigate the effect of
previous COVID-19 infection on various hematological parameters in patients
with active dengue infection. To investigate previous Covid-19 infection. Effect
of 19 infections on morbidity in patients with active dengue infection,
evaluation of days of hospital stay, platelet transfusions, etc.
Methods: A total of 189 patients were
included in our study. The mean age was comparable between the two groups. Group
A patients had a higher mean platelet count [0.68200.00 ± 0.28153.33 x106/cumm]
than Group B patients [0.54181.21 ± 0.31792.06 x106/cumm]. Group A had
substantially shorter hospital stays, averaging 0.380.83 days versus 3.213.24
days for Group B. In addition, Group A received a substantial reduction in
platelet transfusions. Results. Patients with a previous history of COVID 19
infection had significantly lower circulating lymphocyte and monocyte counts,
with lymphocytopenia previously described in patients coinfected with SARS
CoV-2. However, patients with no history of previous covid-19 infection had
substantially lower levels of monocytes and lymphocytes compared to those
without a history.
Conclusion: Our research indicates that
patients with a prior history of COVID-19 infection have reduced dengue
mortality. Patients with previous COVID-19 infections had higher platelet
counts, shorter hospital stays, and fewer platelet transfusions than patients
with no history of COVID 19 infection.
Author (s) Details
Deval Brajesh Dubey
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Swati Agnihotri
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Shilpa Ulhas Vahikar
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Shaila Kumari Mitra
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Kanchan Srivastava
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Amresh Kumar Singh
Department of Microbiology, BRD Medical
College, Gorakhpur, India.
Ravikant Verma
Department of Pathology, BRD Medical
College, Gorakhpur, India.
Please see the book here:- https://doi.org/10.9734/bpi/dhrni/v4/2012
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