The current study investigates the in vitro antioxidant activity and in vivo anti-wrinkle effects of a combined ethanolic leaf extract of Lavandula angustifolia and Nerium oleander on laboratory mice. Antioxidant potential was evaluated using assays such as the hydrogen peroxide scavenging method. The combined extract IC50 value was found to be 17.96±2 which is comparable to standard Ascorbic acid (19.95±2). The in vivo anti-wrinkle activity was assessed by topically applying the extract to the UV-exposed skin of laboratory mice over a specified period. Key indicators such as wrinkle reduction and improvements in skin appearance were monitored and the results were tabulated in Table 13. The results demonstrated that the combined leaf extract exhibited significant antioxidant activity, suggesting its potential to mitigate oxidative stress. Furthermore, the in vivo application significantly improved skin parameters, confirming its efficacy in reducing wrinkle formation. These findings highlight the potential use of this plant-based formulation in cosmetic and therapeutic applications for skin health.
Author
(s) Details
K. V.
Naga Lakshmi
Acharya Nagarjuna University, India and Galgotias University,
Greater Noida, India.
SK.
Abdul Rahaman
Galgotias University, Greater Noida, India.
Devanaboyina
Narendra
VJ’s College of Pharmacy, Diwancheruvu, Rajahmundry, Andhra
Pradesh, India.
Please see the book here:- https://doi.org/10.9734/bpi/rpbs/v5/5740
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