Synthesis and Applications of Xanthate Esters | Chapter 8 | Chemistry and Biochemistry: Research Progress Vol. 1

We herein present a base-induced cycloaddition of active methylene isocyanides like tosyl methyl isocyanide and ethyl isocyanoacetate with xanthate esters for the synthesis of 5-(alkoxy)-4-(tosyl/ethoxycarbonyl)-1,3-thiazoles in DMF. In addition, we have explored xanthate esters as alkylating agents for amines in the presence of an acid catalyst. Finally, the reaction between xanthate esters and aryl methyl isocyanides produced carbamothioates in the presence of a base in DMF.

 

Author (s) Details

 

Toreshettahally R Swaroop
Department of Studies in Organic Chemistry, University of Mysore, Manasagangotri, Mysuru – 570 006, Karnataka, India.

 

Rajaghatta N Suresh
Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru – 570 006, Karnataka, India.

 

Muddegowda Umashankara
Department of Chemistry, Karnataka State Open University, Muktagangotri, Mysuru - 570 006, Karnataka, India.

 

Kanchugarakoppal S Rangappa
Institution of Excellence, University of Mysore, Manasagangotri, Mysuru - 570 006, Karnataka, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/cbrp/v1/3943