Aims: The aim of this chapter is to describe in some detail the evolving concept that Kleine Levin syndrome (KLS), is a neuropsychiatric disorder rather than a rare periodic sleep syndrome.
Methodology: A literature search for papers describing psychiatric
features in patients with classical KLS as well as Atypical KLS was performed
and the psychiatric characteristics of the cases described were divided into
those noted before the onset of KLS typical sleep attacks, those noted during
attacks and de-novo psychiatric morbidity emerging after a long remission from
sleepiness attacks.
Results: Psychiatric morbidity is an essential part of KLS besides
the classical repeated sleepiness attacks. Its presence significantly
contributes to the impaired life quality of the affected youngsters during
their prime time of life as well as their families. Moreover, the presence of
psychiatric morbidity may significantly delay the diagnosis of KLS. Recent data
suggests that psychiatric morbidity in KLS, in particular bipolar disorder, may
be linked to early-life morbid events.
Conclusion: Awareness of the role of psychiatric morbidity as an
associated feature of a rare sleep disorder may shorten the time to definite
diagnosis of KLS, avoid unnecessary tests and sometimes, prolonged
hospitalizations in psychiatric institutes.
Author
(s) Details
Natan Gadoth
Department of Neurology, Ma’ayanei HaYeshua Medical Center, Israel and The
Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Please see the book here:- https://doi.org/10.9734/bpi/msti/v5/4220
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