The present study was conducted in a tertiary care teaching
hospital to evaluate the role of FNAC and CNB in diagnosis of suspicious breast
cancer by keeping mastectomies- surgical excision (SE) as gold standard. Breast
cancer is the commonest female malignancy worldwide. The management of breast
carcinoma relies heavily on the diagnostic parameters. Over the years there has
been a steady decline in the usage of fine needle aspiration cytology (FNAC)
over more popular core needle biopsy (CNB). This was a prospective study done
in the department of Pathology of a tertiary care teaching hospital catering to
the urban as well as rural population in northern part of India. A total of 60
patients were subjected to simultaneous on site FNAC and CNB. Histopathological
correlation (SE) was available in half of the cases only (30 cases). While the
Cytological grading was done according to Robinson grading system; the
histopathological grading was done by Nottingham Modification of Scarff-Bloom
Richardson method. FNAC diagnosed 29 cases whereas CNB diagnosed only 26 cases
as malignant with 3 cases signed out as non-diagnostic for malignancy owing to
non-sampling from the representative areas. On comparing, FNAC and CNB;
agreement was not statistically significant (p=0.14) Comparison of CNB and SE;
in 17 cases agreement were noted for both CNB and SE and statistically the
values were highly significant (p=0.0001). On comparison of FNAC and SE in 13
cases agreement was noted for both FNAC and SE and the data was statistically
significant (p=0.035). It is concluded that FNAC gives 100% results, it is
quite reliable investigation and CNB should be done as an adjunct if needed
especially for grading of the tumor and for immunohistochemistry.
Author(s) Details:
Parul Garg,
Department of Immunohematology and Blood Transfusion, GGS Medical
College and Hospital, Faridkot, India.
Harjot
Kaur,
Department
of Pathology, SGRDIMSR, Sri Amritsar, India.
Neetu Kukar,
Department of Immunohematology and Blood Transfusion, GGS Medical
College and Hospital, Faridkot, India.
Ishwer Tayal,
Department of Forensic Medicine and Toxicology, GGS Medical College
and Hospital, Faridkot, India.
Please see the link here: https://stm.bookpi.org/ANUMS-V6/article/view/13356
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