Thursday, 14 December 2023

A Review on Different Animal and Human Studies to Evaluate the Safety of Inhalation of Propylene Glycol in E-Cigarettes | Chapter 11 | Advanced Concepts in Pharmaceutical Research Vol. 3

 This episode aims to evaluate the security of inhalation of propylene glycol in e-cigarettes. In recent age, e-cigarettes have become more and more popular. Photoelectric cigarettes, or "e-cigarettes," are a safe substitute for smoking use in tobacco produce or as a tool for ending smoking. However, the FDA trusts that e-cigarettes are just as hazardous as traditional cigarettes. Instead, the American Union of Public Health Physicians' Smoking Control Task Force has established that e-cigarettes closely resemble Nicotine Substitute Therapy schemes. All animal and human research that investigated the effect of PG breathing concluded that PG did not perform to constitute a important risk via the breathing route. In fact, in several of these animal troubles, the PG doses employed were above in e-cigarettes and had no deleterious results. However, no human investigations have existed conducted at the level of e-smoke concentrations. This review sheds some light on the security implications of PG breathing, particularly as it has connection with e-cigarette concentration, as manifested in animal research. Since the plurality of the findings introduced from animal studies, the data can be appropriated to launch human studies to determine the short and long-term energy impacts of propylene glycol in e-cigarettes. The human physiology is different as distinguished to the animal physiology. Thus, further human studies using PG concentrations akin to that in e-cigarettes need to be conducted to establish the short term and enduring safety of inhalation of PG from e-cigarettes.

Author(s) Details:

Karyn I. Cotta,
Department of Pharmaceutical Sciences, South University School of Pharmacy, Savannah, GA, USA.

Stephen C. Dyar,
Department of Pharmaceutical Sciences, South University School of Pharmacy, Savannah, GA, USA.

Mohammad N. Uddin,
Mercer University, College of Pharmacy, Atlanta, GA, USA.

Please see the link here: https://stm.bookpi.org/ACPR-V3/article/view/12712

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