Diagnosis of Rare Synchronous Pleural and Peritoneal Mesothelioma in a Domesticated Canine | Chapter 3 | Contemporary Research and Perspectives in Biological Science Vol. 2

This paper reports a rare incidence of invasive mesothelioma in both thoracic and peritoneal cavities of a two and a half year old Labrador Retriever dog and its diagnosis by cytological analysis, radiography and ultrasonogram. Malignant mesotheliomas most often affect the pleura and tend to spread locally within the originating cavity. Mesotheliomas are already rare diseases, and cases with synchronous pleural and peritoneal involvement are scarce in the literature. A male Labrador Retriever dog of two years and six months old was presented to the Teaching Veterinary Clinical Complex Veterinary College and Research Institute, Tirunelveli (Tamil Nadu, India) with the complaint of the distended ventral abdomen, respiratory distress, and exercise intolerance since 4 months and hyporexia since 7 days. The case was treated with parenteral administration of amoxicillin and cloxacillin @ 22 mg/kg b.wt. to prevent complications like peritonitis, furosemide @ 4 mg/kg b.wt. to reduce the ascites in the abdomen, prednisolone @ 0.5 mg/kg b.wt. to reduce neoplastic response (lymphocytosis), multiple amino acids (Astymin®) to alleviate hypoalbuminemia. Therapeutic options for mesothelioma include surgical resection, radiotherapy, and chemotherapy, though a low incidence of the cases in dogs leads to difficulty in the assessment of the therapeutic efficacy of drugs.

 

Author (s) Details

S. Saravanan
Department of Veterinary Medicine, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Tirunelveli-627 358, India and Department of Veterinary Public Health and Epidemiology, Veterinary College and Research Institute, Tamil Nadu Veterinary & Animal Sciences University (TANUVAS), Namakkal-637 002, India.

 

V. Kumar
Department of Veterinary Pathology, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Tirunelveli-627 358, India.

 

R. Ramprabhu
Department of Veterinary Clinical Medicine, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Chennai, Tamil Nadu, India.

 

R. C. Sundararajan
Department of Veterinary Medicine, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Tirunelveli-627 358, India.

 

_{Please see the book here:- https://doi.org/10.9734/bpi/crpbs/v2/2290}