2-Aminoaryl Benzimidazoles towards Potent Antimicrobial Agents| Chapter 2 | Recent Developments in Chemistry and Biochemistry Research Vol. 6

A series of 2-aminoarylbenzimidazoles (3a-l) compounds were screened for their in vitro antimicrobial properties. In the current work, efforts to synthesize 2-aminoarylbenzimidazole derivatives with strong antibacterial activity have been outlined. Xanthomonas campestris, Escherichia coli, Bacillus cereus, Bacillus megaterium, and a fungal strain called Candida albicans were the four microbial strains used to test the prepared compound’s antimicrobial activities. Biological evaluation studies of these 2-aminoarylbenzimidazole derivatives have demonstrated that a number of the tested compounds exhibit moderate to good in vitro antimicrobial activities. The compounds 3a, 3b, 3i, 3j, and 3l exhibited outstanding inhibitory activity. The present study offers an intriguing profile to support experimental studies, mainly in the field of antimicrobial research.

 

Author (s) Details

S. Aravind
Department of Chemistry, University College of Science, Saifabad, Osmania University, Hyderabad, Telangana, India.

 

S. N. Murthy Boddapati
Department of Chemistry, Sir C R Reddy College, PG Corses, Eluru, A.P., India.

 

Surinderpal Singh
Department of Chemistry (H&S), CMR Engineering College, Kandlakoya, Hyderabad, Telangana, India.

 

T. Kiran Kumar

Department of Natural Products & Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology Tarnaka, Hyderabad, Telangana, India.

 

T. Somasekhar
Department of Natural Products & Medicinal Chemistry, CSIR-Indian Institute of Chemical Technology Tarnaka, Hyderabad, Telangana, India.

 

K. A. Emmanuel
Department of Chemistry, Y.V.N.R Government Degree College, Kaikaluru, A.P., India.

G. Giri Prasad
Department of Chemistry, A.G & S.G. Siddartha Degree College, of Arts and Science, Vuyyuru, Andhra Pradesh, India.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/rdcbr/v6/1929