Background: Eosinophilic oesophagitis is a chronic oesophageal disease that is driven by the immune system. It is defined histologically by mostly eosinophilic inflammation and clinically by symptoms resembling oesophageal dysfunction. Allergens have a significant part in causing this illness. Being an immunologically active organ, the oesophagus can draw in eosinophils in reaction to a variety of triggers.
Aim: The present study highlights about last guidelines
about management of Eosinophilic Oesophagitis.
Methods: Numerous nations outside of Africa have recorded
cases of eosinophilic oesophagitis, with men between the ages of. 20 and 30 and
city dwellers having a higher frequency. There are several disorders linked to
this problem, the most significant of which being gastroesophageal reflux
disease (GERD).
Results: From a paraclinical point of view, patients have a
peripheral eosinophilia, and diagnostic certainty is realized by performing
upper endoscopy with biopsy. The recommended treatment has 3 stages, namely
diet, drug therapy (such as fluticasone propionate, budesonide and proton-pump
inhibitors) and investigations such as upper endoscopy.
Conclusion: The article aims to highlight recent
recommendations in international guidelines for the management of eosinophilic
oesophagitis, as well as to review its clinical manifestations, genetics,
immunopathogenesis diagnosis and treatment. A deeper understanding is needed to
inform clinical decisions regarding optimal disease follow-up and the use of
long-term maintenance therapy.
Author(s) Details:
Roxana Elena Mirica,
Department of Gastroenterology, University of Medicine and Pharmacy Carol Davila Bucharest, Regina Maria Private Healthcare Network, Bucharest, Romania.
Please see the link here: https://stm.bookpi.org/ANUMS-V10/article/view/13923
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