Reframing Vulvar and Perineal Dermatoses across the Female Life Course: Integrating Clinical Insight, Biological Innovation, and Sociocultural Context | Chapter 4 | New Horizons of Science, Technology and Culture Vol. 9

 

Vulvar and perineal dermatoses comprise a heterogeneous spectrum of inflammatory, autoimmune, infectious, and neoplastic conditions that affect women across all stages of the female life course. Despite their frequency and clinical impact, these disorders remain under-recognised and are frequently misdiagnosed due to overlapping morphologic patterns, symptom non-specificity, sociocultural barriers to genital examination, and limited formal training in vulvar disease. Diagnostic delay contributes to chronic symptoms, architectural change, sexual dysfunction, and, in selected conditions, malignant transformation.

 

This chapter adopts a life-course framework to examine how physiologic transitions, including hormonal fluctuation, immune modulation, epithelial barrier dynamics, microbiome variation, and evolving environmental exposures, can shape disease susceptibility and phenotype expression from infancy through postmenopause. Major inflammatory dermatoses, particularly lichen sclerosus, lichen planus, psoriasis, and contact dermatitis, are analysed with emphasis on structured diagnostic reasoning, clinicopathologic correlation, appropriate indications for biopsy and patch testing, longitudinal management strategies, and principles of surveillance.

 

In parallel, the chapter integrates emerging scientific and technological advances that are reshaping the field, including developments in immunopathogenesis, molecular characterisation, microbiome research, non-invasive imaging, digital health tools, and artificial intelligence–assisted diagnostic approaches. Cultural and healthcare-system factors influencing presentation, access, and outcomes are also examined, with attention to disparities and variation across populations.

 

By synthesising contemporary evidence within an interdisciplinary yet clinically grounded framework, this chapter bridges fundamental biology and specialist practice while outlining future directions for research, innovation, and improved care in vulvar and perineal dermatoses.

 

 

Author(s) Details

Mariam Sherif Mohamed
Near East University, Nicosia, Cyprus.

 

Panayoti Bachkangi
Lothan Hospital, Kuwait and University of Leicester, United Kingdom.

 

Please see the book here :- https://doi.org/10.9734/bpi/nhstc/v9/7216

Effectiveness of Nursing Post-discharge Guideline on Life Quality among Menopausal Women Undergoing Uterine Prolapse Surgery | Chapter 9 | Current Innovations in Disease and Health Research Vol. 6

 Background: The term "uterine incision" refers to any medical procedure on a woman's generative system. The quality of history of menopausal women maybe impacted by uterine lower a, which can likewise increase maternal morbidity and death. The symptoms and asperity of uterine prolapse decide the course of treatment.Aim concerning this Study: To assess the Effectiveness of Nursing Post-discharge Guideline on Life Quality with Menopausal Women Undergoing Uterine prolapse Surgery.Research Design: A quasi-exploratory design was used.Research Setting: The study was completed activity at gynecological outpatients' clinics owned by Ain Shams University hospitals.Sampling: 210 menopausal wives who were scheduled for abscission and had uterine prolapse in the second, tertiary, or fourth point made up the resolved to do something sample. The pre-test interviews were conducted in outpatient hospitals, and the post-surgery interviews were administered three months following discharge during the nursing home's outpatient area follow-up.Tools: The study variables were calculated using three different mechanisms. First tool: a orderly questionnaire for private and health news. A questionnaire to assess information of uterine prolapse abscission is the second tool. Tool (3). To determine the quality of existence in the bio-psychosocial and tangible domains, the World Health Organization developed the WHOQOL-BREF.Results: Indicated a information difference 'tween the pre-and post-test that was statistically significant. Additionally, following the discharge direction, there was a statistically important association between sure elements of the tangible quality of existence domain.Conclusion: The gaining nourishment by suckling post-discharge approach led to improvements in many fields of life status.Recommendations: For menopausal women sustaining uterine prolapse medical procedure, a continuous occasional nursing care routine should be executed.

Author(s) Details:

Randa Mohamed Abobaker,
Maternal and Child Health Nursing Department, Northern College of Nursing, Arar City, Kingdom of Saudi Arabia.

Hanay Huwaidi Mohammed Alanzi,
Northern College of Nursing, Arar City, Saudi Arabia.

Asmaa Saber Ghaly,
Faculty of Nursing, Alexandria University; College of Applied Medical Sciences, King Faisal University, Saudi Arabia.

Nermine Mohamed Elcokany,
Faculty of Nursing, Alexandria University; College of Applied Medical Sciences, King Faisal University, Saudi Arabia.

Magda Mubarak Merghani,
Nursing Department, College of Applied Medical Sciences -Hafr Al-Batin University, Saudi Arabia.

Rawhia Salah Saleh Dogham,
Nursing Department, College of Applied Medical Sciences -Hafr Al-Batin University, Saudi Arabia.

Please see the link here: https://stm.bookpi.org/CIDHR-V6/article/view/11844

A Brief Study about Menopause and Gynaecological Malignancy | Chapter 1 | Current Practice in Medical Science Vol. 7

 

 Untimely menopause can happen because of disease treatment. Cervical disease is the most well-known gynecological malignant growth. Constant HPV disease is more normal in postmenopausal ladies. In postmenopausal ladies, HPV immunization plays no part in essential cervical disease anticipation. Cervical disease side effects in postmenopausal ladies are tragically vague and related with co-morbidities. Thus, each indication of cervical malignant growth in a postmenopausal lady ought to be explored completely. Among every single gynecologic disease, ovarian malignant growth is the main source of death. Most of postmenopausal ladies with ovarian malignant growth present with questionable side effects and are in a high level phase of the illness at the hour of show. In the United States, endometrial disease is the most regular gynecologic danger. Most of endometrial carcinomas are identified early and have a positive visualization. However vulvar and vaginal malignant growths are unprecedented, they are normal in postmenopausal ladies. Any postmenopausal lady who has been tingling for quite a while, has a pervaginal release, or has a vulva or vaginal ulcer ought to be assessed completely. So principal objective of this composing is to mindful the gynecological oncologists about the extraordinary parts of gynecological diseases in menopausal lady.

Author(s) Details:

Sabera Khatun,
Department of Gynaecological Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Jannatul Ferdous,
Department of Gynaecological Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Please see the link here: https://stm.bookpi.org/CPMS-V7/article/view/7832

Prevalence of Gene Polymorphism for Menopausal Women with Cardiovascular Disease: A Study from Punjab, India | Chapter 20 | Issues and Developments in Medicine and Medical Research Vol. 6

 The purpose of this study was to determine the prevalence of the +276 G/T polymorphism in the AdipoQ gene in menopausal Punjabi women with and without a family history of cardiovascular disease (CVD), as well as whether a positive family history of CVD has any specific independent effect on cardiovascular disease in menopausal Punjabi women. The Sri Guru Ram Das Institute of Medical Sciences and Research in Amritsar, Punjab, recruited 265 menopausal women with CVD as cases and 258 menopausal women without CVD as controls (India). The relationship between ADIPOQ SNPs, adiponectin levels, and cardiometabolic illnesses could be hampered by a number of causes or mechanisms. Family history prevalence varies depending on the age at which it is assessed. CVD aggregation in families may be linked to the accumulation of specific risk factors, such as those listed above, or specific behaviours, like as smoking and alcohol consumption, which may be influenced by hereditary and environmental variables. In cases with positive familial h/o of CVD, the TT genotype of recessive model of inheritance gave a 6-fold increased risk of CVD compared to controls, according to the study. The prevalence of the TT genotype was observed to be higher in cases than controls in both women with and without family history of CVD. To reduce illness burden, new treatment strategies can be created. Furthermore, there is a pressing need for a stronger public health-care system.

Author(S) Details

Jyot Amrita
Department of Biochemistry, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar, Punjab-143001, India.

A. J. S. Bhanwer
Department of Genetics, Sri Guru Ram Das University of Health Sciences, Amritsar, Punjab-143001, India.

A. P. Singh
Department of Anesthesia, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India.

View Book:- https://stm.bookpi.org/IDMMR-V6/article/view/5694

Assessment of Quality of Life and It’s SocioDemographic Correlates in Post Menopausal Women| Chapter 10 | Technological Innovation in Pharmaceutical Research Vol. 9

 Introduction: Psychological, somatic, and vasomotor problems, as well as sexual dysfunction, can accompany menopause. Current health-care paradigms, on the other hand, are blind to the fact that these symptoms have a substantial impact on a woman's personal and social functioning, and hence her quality of life. As a result, the purpose of this study is to identify postmenopausal women's quality of life as well as the socio-demographic factors that influence quality of life. Materials and Methods: 105 females aged 45 to 65 years old were questioned using the MENQOL questionnaire in a cross-sectional study in an urban slum region. Participants in the study were asked about their age, menopausal duration, education, occupation, job status, family income, marital status, and number of children. The participants in this study had an average age of 54.13 4.05 (45-62) years. Twenty percent of the 105 postmenopausal women who participated in the study were illiterate, while 26.7 percent had finished secondary school. The overall MEN-QOL score ranged from 62 to 148, with a mean of 101.3 23.44. Conclusion: Menopause has an impact on a woman's physical and mental health, as indicated by the current study, which discovered that MEN-QOL scores were higher after menopause, indicating a lower quality of life. Age, a lack of education, a lower socioeconomic status, unemployment, and a lack of spouse support all contributed to a poor quality of life.

Author(s) Details

Dr. Purnima Raj
Department of Pharmacology, Late Shri Lakhiram Agrawal Memorial Government Medical College, Raigarh, Chhattisgarh, India.

Dr. Namita Deshmukh
Department of Community Medicine, Dr. Ulhas Patil Medical College, Jalgaon, Maharashtra, India.

Dr. Avinash Borkar
Department of Community Medicine, Dr. Ulhas Patil Medical College, Jalgaon, Maharashtra, India.

View Book :-  https://stm.bookpi.org/TIPR-V9/article/view/2523

Study on Mammographic Breast Pattern in Postmenopausal Women in Ibadan, South-Western Nigeria | Chapter 1 | Issues and Development in Health Research Vol. 1

 The density of mammograms is a powerful predictor of breast cancer. Menopause has a substantial impact on breast pattern and has been shown to have a greater impact on mammographic density reduction than age. The goal of this study was to investigate breast parenchymal density patterns in postmenopausal women in Ibadan and connect them with socio-demographic and anthropometric data. Methodology: This is a retrospective cross-sectional study of 196 postmenopausal women who underwent two screening views on each breast at the University College Hospital Ibadan's Radiology Department. Data was taken from a questionnaire filled out by patients who had a mammogram during the time period under consideration. The mammography reports were matched with the patients' sociodemographic information and analysed using the R statistical software. The women's mean age at menopause was 48.44.6 years, and their mean age at menopause was 55.06.8 years. 82.1 percent of the women had the combined BI-RADS 1 and 2 breast parenchymal patterns, which are linked to a lower risk of breast cancer. The difference in average age at first birth between women with BI-RADS 1 and 2 and women with BI-RADS 3 and 4 was statistically significant (P=0.035). Although not statistically significant, BMI, family and personal history of breast cancer all exhibited a link with breast parenchymal pattern. Conclusion: The study's findings of a low prevalence of dense breast pattern are consistent with earlier findings of a reduced prevalence of breast cancer in African women. The clustering of low mean age at first childbirth, low mean age at menopause, and multi-parity in the majority of the women in this study, in combination with low mammographic density, further supports the significantly lower risk of breast cancer in our study population.

Author (s) Details

O. S. Bassey
Department of Radiology, University College Hospital, Ibadan, Nigeria and Department of Radiology, Nile University of Nigeria, Abuja.

T. O. Soyemi
Department of Radiology, University College Hospital, Ibadan, Nigeria.


A. T. Adeniji-Sofoluwe
Department of Radiology, University College Hospital, Ibadan, Nigeria.

A. O. Adeoye
Department of Pathology, University College Hospital, Ibadan, Nigeria.

O. A. Mosuro
Department of Family Medicine, University College Hospital, Ibadan, Nigeria.

T. S. Akingbola
Department of Hematology, University College Hospital, Ibadan, Nigeria.

O. O. Osofundiya
Department of Radiology, University College Hospital, Ibadan, Nigeria.

G. O. Obajimi
Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria.


A. O. Oluwasola
Department of Pathology, University College Hospital, Ibadan, Nigeria.

M. O. Obajimi
Department of Radiology, University College Hospital, Ibadan, Nigeria.

O. I. Olopade
Department of Medicine, Center for Clinical Cancer Genetics and Global Health, University of Chicago, Chicago, Illinois, USA.


View Book :- https://stm.bookpi.org/IDHR-V1/article/view/2152