Positive Impacts of Olive Oil Enriched with Lycopene on the Plasma Antioxidant and Anti-Inflammatory Status of Hypercholesterolemic Patients | Chapter 2 | Disease and Health: Research Developments Vol. 10

Atherosclerosis is a chronic inflammatory disease that is responsible for several cardiovascular events such as ischemic heart disease, coronary artery disease, peripheral artery disease, and ischemic stroke. Olive oil and lycopene are foods that have potent antioxidant activity. The objective was to determine the effects of consumption of olive oil enriched with lycopene on oxidative stress biomarkers in hypercholesterolemic subjects. The study product sample “lycopene-olive oil” consisted of virgin olive oil enriched with lycopene (350 mg/L). Patients (n = 80) were recruited from the town of Moralzarzal, Madrid, Spain, including healthy men and women with cholesterol levels over 220 mg/dL. The effects of oil enriched with lycopene extract daily intake were examined for 1 month on plasma antioxidant capacity, lipid profile (triacylglycerols, total cholesterol, HDL-C; LDL-C, ox-LDL), biomarkers of oxidative stress, and inflammatory markers related to atherosclerosis risk (C-reactive protein (CRP), IL-6; sDC4L) in subjects with hypercholesterolemia (cholesterol > 220 mg/dL). In the group consuming olive oil-lycopene, significant increases (p < 0.05) in the levels of plasma lycopene concentration (0.146 ± 0.03 versus 0.202 ± 0.04 (µmol/L)), α-carotene (0.166 ± 0.064 versus 0.238 ± 0.07) and β-carotene (0.493 ± 0.187 versus 0.713 ± 0.221) were observed. These results are linked with the increases of plasma antioxidants and decrease in biomarkers of oxidative stress (carbonyl groups, malondialdehyde and 8-hydroxy-deoxyguanosine) observed in the hypercholesterolemic group. In relation to the lipid profile, a significant decrease was observed in the levels of ox-LDL (781 ± 302 versus 494 ± 200), remaining unchanged in the levels of TG, cholesterol, HDL and LDL-C. Regarding inflammatory biomarkers, the levels of CRP and IL-6 decreased significantly. The positive results obtained in this study support the use of olive oil enriched with lycopene to reduce the risk of coronary disease. The results also indicate that triglyceride, cholesterol, LDL, and HDL levels did not change significantly. However, ox-LDL levels decreased significantly only in the group supplemented with lycopene-olive oil. In conclusion, this study suggests that foods containing olive oil and lycopene can significantly contribute to reducing LDL-induced oxidative stress.

 

Author (s) Details

Meryem El Ouardi
Predepartmental Unit of Medicine, Physiology Section, Faculty of Health Sciences, Universidad Jaume I, 12006, Castelló de la Plana, Spain.

 

Guillem Garcia-Llorens
Predepartmental Unit of Medicine, Physiology Section, Faculty of Health Sciences, Universidad Jaume I, 12006, Castelló de la Plana, Spain.

 

Victoria Valls-Belles
Predepartmental Unit of Medicine, Physiology Section, Faculty of Health Sciences, Universidad Jaume I, 12006, Castelló de la Plana, Spain.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/dhrd/v10/5033

Tomato Puree Lycopene: Protective Effects in Atherosclerosis/Heart Diseases | Chapter 8 | Novel Aspects on Pharmaceutical Research Vol. 5

 The working food industrial marquee linked potential presenting investigation on hypolipidemic and antioxidant efficacy of attractive woman puree lycopene has been arose out as a next generation research folio inclined be beneficial for creative start up mission. New generation advantageous position for those selling base nutrition superimposing health claim promoting food crop linked with worth addition is underlined as a new dimension of working foods. In present study the energy claim exploration ability of lycopene rich attractive woman puree as a novel food additive was assessed by animal studies to project hypolipidemic efficacy to defeat risk of selective non-able to be contracted diseases. The data study, interpretation and reviewed research infusion together underlined the efficacy of lycopene (tomato make into paste) in monitoring atherogenesis mechanism through cooperative mode of action of informed specialty countenance (total cholesterol, serum triglycerides, LDL cholesterol and HDL cholesterol) and projected an active gateway to support disease soaked health claim appraisal. Lycopene has several cardiovascular health benefits to a degree antioxidative, anti-inflammatory, antagonistic-atherogenic, cardioprotective, antiplatelet effect, improving endothelial function (nitric group of chemical elements bioavailability and blood flow), metabolic profile (by impairing cholesterol combination) and blood pressure control. The cumulative decrease in total cholesterol of medicated rats (159.99 to 126.40mg/dl), serum triglycerides (114.81 to 107.34mg/dl), LDL cholesterol (40.19 to 32.90mg/dl) and increase in HDL cholesterol (19.99 to 23.87mg/dl) represents hypolipidemic productiveness of tomato smash lycopene. The development of a prototype for CVD to begin a health claim was rationally renovated by the attractive woman puree mass, a practicable source of lycopene with native antiatherogenic efficacy. The human clinical study as a proof tool, concede possibility be the best option for future generations research.

Author(s) Details:

Kavita Mane,
MIT School of Food Technology, MIT Art, Design and Technology University, Rajbaug, Pune, India.

Vasant Pawar,
MIT School of Food Technology, MIT Art, Design and Technology University, Rajbaug, Pune, India.

Please see the link here: https://stm.bookpi.org/NAPR-V5/article/view/11052

Study on Lycopene accumulation in Difference Fruits | Chapter 06 | Emerging Challenges in Agriculture and Food Science Vol. 4

 Lycopene is a substance that has acquired popularity due to its alleged health advantages. decreasing the risk of cancer in several organs, in particular Prostate cancer is the most visible, followed by lung and stomach cancer. Lycopene has also been found to help prevent malignancies of the pancreas, colon, rectal, pharyngeal, oral, and breast. Mouth and milk. The goal of this research is to find out how much lycopene is in fresh fruits like tomatoes (Solanum Lycopersicum), watermelons (Citrullus lanatus var. lanatus), jackfruits (Artocarpus heterophyllus), bananas (Musa acuminata), grapes (Vitis vinifera), oranges (Citrus reticulata), and papayas (Citrus reticulata (Carica papaya). The researchers discovered that lycopene levels in tomatoes (Solanum Lycopersicum), watermelons (Citrullus lanatus var. lanatus), jackfruits (Artocarpus heterophyllus), bananas (Musa acuminata), grapes (Vitis vinifera), oranges (Citrus reticulata), and papayas (Carica papaya) were 104.6990.000, 144.270.001, The greatest lycopene was found in watermelons (Citrullus lanatus var. lanatus), while the least was found in jackfruits (Artocarpus heterophyllus). Lycopene (Lycopene) is a red pigment that can be found in a variety of fruits and vegetables. And is a carotene subunit that is an antioxidant. Lycopene is a vitamin that is good for your health (carotenoids). especially when it comes to skincare.

Author(S) Details

Theeranat Suwanaruang
Faculty of Science and Health Technology, Kalasin University, Thailand.

View Book:- https://stm.bookpi.org/ECAFS-V4/article/view/6405

Recent Advances Regarding the Phytochemical and Therapeutic Benefits of Diospyros kaki Fruit | Chapter 12 | Current Advances in Chemistry and Biochemistry Vol. 5

 Several recent research have proved the health benefits of consuming natural substances. Lycopene and ascorbic acid, two fruit phenolics, have potent antioxidant, anti-inflammatory, antimugenic, and anticarcinogenic properties. Color, moisture, pH, water activity, total phenolic compounds, ascorbic acid, and lycopene concentration were all examined as characteristics related to fruit quality and climatic conditions in this study. Different solvents, such as methanol, ethanol, and water, were used to extract Diospyros kaki cv. chocolate fruits. When considering Diospyros fruits with peel, total polyphenolics of each extract were shown to be higher in methanolic extract and lower in ethanol using the Folin-Ciocalteu method. Significant differences in the amounts of these characteristics were discovered across geographic regions. The findings suggest the use of Diospyros kaki cv. chocolate fruits, a Portuguese cultivar, as a functional food with strong antioxidant capacity that may protect humans from oxidative stress.

Author(s) Details

Ana F. Vinha
LAQV/Requimte, Department of Chemical Sciences, Faculty of Pharmacy of University of Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal and FP-ENAS (UFP Energy, Environment and Health Research Unit), CEBIMED (Biomedical Research Centre), University Fernando Pessoa, R. Carlos da Maia, 296, 4200-150 Porto, Portugal.

Marta O. Soares
Drug Discovery, Delivery and Toxicology, IINFACTS /CESPU, Paredes, Portugal.

Marisa Machado
Drug Discovery, Delivery and Toxicology, IINFACTS /CESPU, Paredes, Portugal.

View Book :- https://stm.bookpi.org/CACB-V5/article/view/1094