Recent Advances in Green Bromination: An Overview | Chapter 2 | Advancements in Science and Technology: Paving the Way to a Sustainable Future

Organobromo compounds occupy a significant place in synthetic organic chemistry serving as intermediate for transforming smoothly into various products with antibacterial, antiviral, antitumor, antifungal properties etc. Bromine is the traditional brominating reagent that is used even today in most laboratories for carrying out bromination in spite of its corrosive, irritating nature and the difficulty level in its usage. Besides bromine, the other brominating reagents commonly used are N-bromosuccinimide, metal bromides along with strong oxidizing agents. In addition, bromination is also accomplished with the use of hypervalent transition metal catalysts. These reagents although may be less hazardous than bromine have other disadvantages i.e. longer reaction time, resulting in the incorporation of large organic waste into the environment and some reagents are carcinogenic in nature. Despite these serious problems associated with brominating reagents, one cannot escape from the process of bromination because of the important synthetic utility associated with bromo derivatives.

Indeed, the various principles of Green Chemistry also advocate the use of non-hazardous, non-toxic, environmentally benign reagents as well as solvents thereby emphasizing issues related to environment, health and safety. Hence, researchers are always interested in exploring green, environmentally friendly routes to brominate the various substrates. Keeping in view the demand for green ways to bromination, it is hereby presented the review article highlighting the various green methods of carrying out the bromination process. This review article definitely will be beneficial to the researcher engaging with the usage of brominated compounds and further will encourage them to explore and add the various environmentally friendly routes to halogenations to the literature of synthesis.

 

Author (s) Details

 

Dr. Deepak Sharma
Chemistry Department, Govt. P. G. College, Ambala Cantt, India.

 

Dr. Abha Chaudhary
Chemistry Department, Govt. P. G. College, Ambala Cantt, India.

 

Dr. Tarsem Kumar
Zoology Department, Govt. P. G. College, Ambala Cantt, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-49473-39-3/CH2