Background: Sickle cell disease consists of a group of inherited hemoglobinopathies affecting multiple organs including the eyes. Ischemia can result from occlusion of vessels by rigid red blood cells with a sickle-shaped appearance.
Aims and objectives: The aim of the study is to report
regression of retina neovascularization and visual outcomes after prophylactic
scatter retina laser photocoagulation for Goldberg stage 3 PSR in a tertiary
private hospital in sub-Saharan Africa.
Methods: A retrospective review of case files of patients
who were treated with prophylactic scatter retina laser photocoagulation
between January 2017 and June 2022 following a diagnosis of PSR in a Eye
Foundation Hospital, Ikeja, Lagos, Nigeria, was done.
Results: A total of 124 eyes of 62 patients with PSR were
seen within the period under consideration. A majority of patients (49 (79.0%))
had hemoglobin (Hb) genotype SC, while 13 patients (21%) were Hb genotype SS.
At presentation, 29 eyes (23.3%) had Goldberg stage 2 PSR, 55 eyes (44.4%) had
Goldberg stage 3 PSR, 27 eyes (21.8%) had stage 4 PSR, and 13 eyes (10.5%) had
stage 5 PSR. All 55 eyes (49.2%) with stage 3 PSR were treated with
prophylactic retina laser photocoagulation. At the patients’ last clinic visit,
34 eyes (61.8%) had the same visual acuity (VA) as at presentation, 11 eyes
(20%) had improvements in VA, while 10 eyes (18.2%) had worse VA. Laser
treatment success (regression of seafan neovascularization) was seen in 50 eyes
(90.9%), while five eyes (8.1%) had unsuccessful laser treatment.
Conclusion: A high percentage (90.9%) of resolution of
retina neovascularization secondary to PSR at stage 3 of Goldberg’s
classification was seen after prophylactic scatter retina laser
photocoagulation in our group of evaluated patients. Most patients (81.8%)
maintained or had improvements in their visual acuities over the period of
follow-up. More clinical research is required to further evaluate outcomes of
laser photocoagulation for PSR. In conclusion, a high percentage (90.9%) of
resolution of retina neovascularization secondary to PSR at stage 3 of
Goldberg’s classification was seen after prophylactic scatter retina laser
photocoagulation in our group of evaluated patients.
Author (s) Details
Oderinlo Olufemi
Eye Foundation Hospital, GRA Ikeja, Lagos, Nigeria.
Bulus Stanley Sano
Department of Ophthalmology, Barau Dikko Teaching Hospital, Kaduna State
University, Kaduna, Kaduna State, Nigeria.
Umeh Victor
Eye Foundation Hospital, GRA Ikeja, Lagos, Nigeria.
Lateefat Oshunkoya
Eye Foundation Hospital, GRA Ikeja, Lagos, Nigeria.
Adekunle Hassan
Eye Foundation Hospital, GRA Ikeja, Lagos, Nigeria.
Please see the book here:- https://doi.org/10.9734/bpi/msti/v4/4154
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