Tuesday, 17 November 2020

Investigating the Prevalence and Risk Factors for Hypertension, Diabetes and Obesity among Lecturers and Support Staff of Bishop Stuart University in Mbarara, Uganda | Chapter 13 | Current Topics in Medicine and Medical Research Vol. 9

 Objective: To evaluate the prevalence and risk factors among teaching and non-teaching staff of Bishop Stuart University of Mbarara-Uganda for hypertension, diabetes and obesity.

Context: Among the Non-Communicable Diseases (NCDs) affecting the developed and developing world are diabetes, hypertension and obesity. These disorders are mostly correlated with older age groups, but data suggests that between 30 and 69 years of age, 15 million of all deaths due to NCDs occur. Recognizing the recent inclusion in the health policy agenda of Uganda of hypertension and diabetes, this study was conducted among university workers in rural areas to provide benchmark information for the design of effective interventions.
Research Design: This was a cross-sectional, institutional-based, descriptive survey design. Location and length of the study: This study was performed between the teaching staff and none of the teaching staff of Mbarara University, Uganda, from 18 April to 6 June 2017.
Methodology: A systematic questionnaire was used to collect data from university staff at their workstations on social demographics and risk factors. Each participant's blood pressure was assessed, and systolic BP>140 and/or diastolic (BP) >90 mmHg was described as hypertension. To assess weight levels, anthropometric measurements (Body Mass Index (BMI) were carried out by weight in Kg) and by height in (M2). Obesity was measured at a BMI of >40. A diabetic level of random blood sugar (RBS) > 200 mg/dl was considered. Epi-info version 7, analysed using SPSS version 19, was used to enter data.
Results: A total of 156 university workers aged 25-75 years of both sexes were interviewed, with a mean age of 42±8 years, of whom 51% were males. About 15% were administrative workers, 55% were teaching employees, 3% were senior lecturers and professors, and 25% were non-teaching employees. The prevalence of hypertension, diabetes and obesity is 7.7%, 16%, and 28%, respectively. But most (60.2%) were also found to be at risk of developing both hypertension and diabetes. Less than 20% of the participants were knowledgeable on causes, signs and symptoms and preventive measures for Hypertension but had moderate knowledgeable of the risk factors, the most frequently mentioned risk by 71% was lack of exercise. Despite the understanding of risk factors, most (61.3%) did not conduct any sort of exercise and 64.1% did not have daily blood pressure tests.A statistically relevant association between those over 40 years of age and hypertension (X2=5.82, P=0.015, OR= 4.2) was also seen in the study. The risk of diabetes has also risen with age. Compared to those less than 40 years of age, lecturers aged 40 years and over were 5.6 times more likely to have diabetes (OR= 5.6, X2=16, P=0.0005) . More than a third of the applicants. 57/156 (36.5 percent) among their family members reported a history of HPT. 49 percent and 34 percent, p<0.01). In senior administrative workers and lecturers, the incidence of obesity and overweight was found higher than in lower system staff.
Conclusion: Hypertension, diabetes and obesity are prevalent conditions among BSU teaching and teaching personnel, but there is insufficient knowledge of risk factors, clinical presentation and preventive strategies. Public health measures recommended for monitoring by university workers are routine physical exercises, frequent body tests and regulated diet. Therefore this study indicates that university workers need high-level awareness campaigns about non-communicable diseases and the need for daily health check-ups.

Author(s) Details

Jordan Amanyire
Department of Public Health, Bishop Stuart University, P.O.Box 9 Mbarara, Uganda.

Mathias Tumwebaze
Department of Public Health, Bishop Stuart University, P.O.Box 9 Mbarara, Uganda.

Mauda Kamatenesi Mugisha
Department of Public Health, Bishop Stuart University, P.O.Box 9 Mbarara, Uganda.

Labani Waswa Bright

Medical Research Council (MRC) P.O.Box 48 Entebbe, Uganda.

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A Detailed Review of Literature on Mercury Toxicity and Treatment | Chapter 12 | Current Topics in Medicine and Medical Research Vol. 9

 Mercury is a poisonous heavy metal that in nature, is widely spread. Fish consumption or dental amalgam results in most human exposure. Mercury appears in many chemical types, with pharmacokinetics that are complex. A broad range of clinical presentations can be induced by Mercury. Mercury toxicity diagnosis can be complicated but can be achieved with fair reliability. Successful clinical toxicity therapies have been defined. No consensus guidelines are currently in place for the diagnosis of mercury excess or overload of other toxic metals. A provoked urine metal production of more than 2 standard deviations above the NHANES reference range is usually considered a positive result by clinicians who specialise in this field. To explain the relationship between provoked urine outcomes and clinical disease and to record clinical outcomes, further research is required.


Author(s) Details

Robin A. Bernhoft
Bernhoft Center for Advanced Medicine, Suite A, 1200 Maricopa Highway, Ojai, California, USA and Los Angeles Center for Advanced Medicine, 2128 Pico Boulevard, Santa Monica, California 90405, USA.

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Medical Scientific Research, Human and Animal Experimentation, and Ethics | Chapter 11 | Current Topics in Medicine and Medical Research Vol. 9

 In contemporary science and medical research, a survey of the moral and ethical conditions is suggested and an alarm clock is rung about the restriction currently placed on the imagination and accountability of the researchers.


Author(s) Details

V. Coulic
Laboratory of Translational Research of the Brussels Free University, Brussels, Belgium.


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A Detailed Study on the Effects of Corona | Chapter 10 | Current Topics in Medicine and Medical Research Vol. 9

 The Covid-19 crisis that we are witnessing right now has been a significant turning point in the lives of many of us, but it will definitely bring a drastic change in our lives. Through adaptation and harmony, we will live well enough that we can alter the way we interact with the same effect on us. But who's responsible for a case like that? Human beings are the key. And there is no need for one to provide a research paper on this. We have to handle nature better if we want a better life. That is Corona's message to us as Corona is a part of nature as well. Some of these behavioural improvements needed to conserve nature and the need to take immediate action to correct the wrongs done to nature are illustrated in the current article, otherwise a tiny creature such as a virus will bring the world to a standstill.


Author(s) Details

Dr. Shobha Misra
Department of Community Medicine at P D U Medical College, Rajkot, India.

Bhakti Sharma

Zydus Medical College, Dahod, India.

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Discussing the Diffusion Tensor Imaging without Complex Statistical Analysis Could Be Helpful for Diagnosis | Chapter 9 | Current Topics in Medicine and Medical Research Vol. 9

 Objective: The visualisation of fibre tracts in the brain is possible thanks to rapidly evolving technology. Yet data processing and analysis are becoming more complicated with the latest technologies. Currently, interpretations are mainly in-group research in these areas and are therefore not useful on the basis of individual patient assessments. In this regard, we investigated our cases with diffusion tensor imaging (DTI) and attempted to demonstrate whether or not the data could simply be interpreted by the eye of the radiologist.

Materials: Our study consisted of 31 cases with 3 Tesla Magnetic Resonance Imaging (MRI) units that were evaluated in our middle. For ischemia, posttraumatic axonal injury, congenital malformation, neoplasia, autism, mental retardation and epilepsy, Cranial DTI studies have been conducted. In neoplasia and ischemia cases, cranial DTI was performed to show successful fibre tracts and was used in other cases to classify any gross anomaly in micro structural anatomy in addition to standard traditional MRI. Along with fused traditional T1 weighted 3D high-resolution images and FA charts, DTI images were assessed. DTI was done during the patients' first administration.
Results: DTI-FA images showed us important signal changes secondary to Wallerian degeneration in two cases, in addition to the chronic ischemic focus in patients with ischemia. While isointense in traditional series, FA values showed decreased values at the levels of axonal discontinuity in traumatic brain injury cases. In congenital malformation cases, major interaction and projection fibre defects were visualised in both fused 3D-DTI images and FA map images. Displacement, penetration, fibre degradation in cases of neoplasia have been clearly visualised. However, in all patients diagnosed with motor mental retardation, epilepsy or neuropsychiatric conditions, any objective abnormality has not been recorded.
Conclusion: In conclusion, although it does not provide useful concrete and case-specific information to radiologists, especially in cases of microstructural abnormalities such as neuropsychiatric disorders, epilepsy and motor-mental retardation, it is possible to obtain diagnostic information from DTI-FA maps and 3D-trac-tography images in most cases of organic pathologies. Indeed, statistical analysis programmes currently used could demonstrate microstructural anomalies as well as expand steadily and this field is the subject of ongoing study.

Author(s) Details

Duzgun Yildirim
Department of Medical Imaging, Acibadem University, Vocational School of Health Sciences, Istanbul, Turkey.

Deniz Alis
Acibadem Maslak Hospital, Department of Radiology, Istanbul, Turkey.

Gokhan Kuyumcu
Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Istanbul, Turkey.

Selim Bakan
Istanbul University, Cerrahpasa Medical Faculty, Department of Radiology, Istanbul, Turkey.

Özlem Güngör

Istanbul Sancaktepe Prof. Dr. Ilhan Varank Training and Research Hospital, Department of Radiology, Istanbul, Turkey.

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Investigation of Hepatitis B and C virus Co-Infection in Pregnancy at a Tertiary Hospital, Yenagoa, Bayelsa State, Nigeria | Chapter 8 | Current Topics in Medicine and Medical Research Vol. 9

 A fair proportion of liver diseases worldwide are caused by hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Co-infection of both viruses is not rare since identical modes of transmission are shared by the two viruses. The aim is to establish the coinfection of the Hepatitis B and C viruses in pregnancy, their seroprevalence and clinical-epidemiological correlates. This is a cross sectional descriptive analysis. After pre-test counselling and obtaining consent from them, two hundred and twenty (220) consecutive healthy pregnant women attending the hospital antenatal booking clinic who met the inclusion requirements were recruited into this research. This has been tested with commercially available in vitro diagnostic kits (one stage test strips) for both HBsAg and anti-HCV antibodies. Data was gathered via a questionnaire. SPSS (statistical package for social sciences) 22 statistical package (SPSS Inc., Illinois, U.S.A) was used for data entry and analysis. P value less than 0.05 was taken as important. The mean age was 28.8 years ± 5.2 for the pregnant women surveyed, while the mean parity was 1.20 ± 1.16. Of the 220 pregnant women recruited, 4.6% (n=10) were seropositive for surface hepatitis B antigen (HBsAg), while 2.7% (n=6) were seropositive for viral hepatitis C (anti-HCV) antibodies. There was 0% co-infection with hepatitis B and C viruses during pregnancy. The major risk factors for HBsAg seropositivity (p<0.05) were multiple sexual partners and female circumcision. None of the risk factors were significantly associated with the seropositivity of hepatitis C viral antibodies. The rate of co-infection of hepatitis B and C viruses in pregnancy in our obstetrics population is infinitesimal. However, regular screening for infection with the Hepatitis B virus and support for active and passive immunisation of seropositive pregnant women's infants is recommended.


Author(s) Details

Dr. E. L. Kotingo
Department of Obstetrics and Gynaecology, Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria.

Dr. D. O. Allagoa

Department of Obstetrics and Gynaecology, Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria.

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OSPE, OSVE and OSCE in Anatomy | Chapter 7 | Current Topics in Medicine and Medical Research Vol. 9

 We may wonder how it is possible to apply OSPE (objective structured practical examination), OSVE (objective structured viva examination) and OSCE (objective structured clinical examination) in Anatomy. These are the different evaluation approaches which are focused on objectivity. These approaches are accepted internationally and are applied worldwide because they carry out impartial assessment of students in clinical and para-clinical subjects. There is an immense scope of human anatomy to test the cognitive and psychomotor fields of students. The use of OSPE, OSVE and OSCE in various branches of anatomy will allow us to evaluate students effectively and at a satisfactory level. To evaluate the skills and knowledge of 1st M.B.B.S students, OSPE can be applied in microanatomy, OSVE in table viva, and OSCE in living anatomy. In the present chapter, students were introduced to two evaluation methods in microanatomy (spots with unstructured viva and OSPE-objective organised practical examination) for a routine evaluation process. In the form of a questionnaire, feedback was taken and statistical analysis was performed. The outcome shows that objective organised practical research increases objectivity and decreases subjectivity relative to traditional viva.


Author(s) Details

Dr. A. S. Sabnis
Department of Anatomy, M.G.M. Medical College, Navi- Mumbai- 410209, MS, India.

Dr. Y. Bhosale

Department of Anatomy, Seth G.S. Medical College, Mumbai- 400012, MS, India.

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