Commercial Uses of Different Lipid-Based Nanovesicles in Current Scenario | Chapter 9 | Pharmaceutical Research: Recent Advances and Trends Vol. 5

 

Nanoparticles have emerged as a promising alternative to conventional methods in various fields, including the pharmaceutical industry. They have been used to preserve drugs with potential therapeutic benefits, find new uses for old medicines, and deliver biopharmaceuticals. Despite the advancements in drug delivery systems, conventional methods often face significant challenges, including poor solubility, limited bioavailability, and systemic side effects. These limitations hinder the effective delivery of both hydrophilic and lipophilic therapeutic agents, resulting in suboptimal treatment outcomes. Lipid-based nanovesicles (L-NVs) have emerged as a promising solution to these challenges, offering enhanced stability, targeted delivery, and improved therapeutic efficacy. However, the transition of L-NVs from laboratory research to commercial application is fraught with regulatory hurdles, manufacturing complexities, and the need for rigorous safety and efficacy assessments. This chapter introduces the extensive range of L-NVs currently available, focusing on the latest generation of non-liposomal L-NVs, and highlighting their similarities and differences.

 

Author(s) Details

Shibangi Mukhopadhyay
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Nidhi Agrawal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Meenakshi Jaiswal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

S.K. Lanjhiyana
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Alpana Ram
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Rashmi Dewangan
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Rajkumar Sironiya
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/prrat/v5/1816

Comprehensive Review on Drug-Loaded Niosomes: A Promising Nanocarrier-based System | Chapter 2 | Pharmaceutical Research: Recent Advances and Trends Vol. 10

Vesicular drug delivery systems, niosomes are currently innovative delivery systems that encapsulate hydrophilic and hydrophobic drugs into the core and the bilayer of these niosomes. Niosomes are composed of non-ionic surfactants and differ from traditional liposomes by having chemical stability and smaller drug leakage. Targeted drug delivery with enhanced therapeutic efficiency is achieved, as well as a reduction in side effects and increased drug presence at the target site. Preparation of niosomes, their types, advantages and drawbacks are discussed in this review.

 

Author (s) Details

 

V. Himabindu
Department of Pharmaceutics, Anurag Pharmacy College (Affiliated to JNTUH, Hyderabad), Kodad, Telangana, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/prrat/v10/3271

Liposomal Vaccines: Recent Advances in Vaccine Delivery Systems| Chapter 11 | Current Progress in Medicine and Medical Research Vol. 3

 Liposomal vaccines are by artificial means prepared microscopic vesicles containing a lipid bilayer which can epitomize vaccines for various diseases. Liposomes play an main role in vaccine growth as vaccine carrier busses for many diseases like sickness, hepatitis, influenza and various cancers. The hydrophilic compounds like proteins, peptides, haptens, and deoxyribonucleic acid can be incorporated inside the inner aqueous scope of the liposomal vesicles, whereas the hydrophobic compounds like antigens, something which incites activity and linker molecules can be ascribed to the phospholipid bilayer or to the liposome surface by chemical linking. This phase focuses primarily on liposomal vaccine electronics regarding the traits, stability, methods of readiness, applications, advantages and difficulties of liposomal vaccines.

Author(s) Details:

V. Ashok,

Shri Sathya Sai Medical College and Research Institute, Sri Balaji Vidyapeeth (Deemed to be University), Puducherry, India.

P. J. Padmini,

Saveetha Medical College and Hospital, SIMATS Deemed University, Chennai, India.

Please see the link here: https://stm.bookpi.org/CPMMR-V3/article/view/11244