Commercial Uses of Different Lipid-Based Nanovesicles in Current Scenario | Chapter 9 | Pharmaceutical Research: Recent Advances and Trends Vol. 5

 

Nanoparticles have emerged as a promising alternative to conventional methods in various fields, including the pharmaceutical industry. They have been used to preserve drugs with potential therapeutic benefits, find new uses for old medicines, and deliver biopharmaceuticals. Despite the advancements in drug delivery systems, conventional methods often face significant challenges, including poor solubility, limited bioavailability, and systemic side effects. These limitations hinder the effective delivery of both hydrophilic and lipophilic therapeutic agents, resulting in suboptimal treatment outcomes. Lipid-based nanovesicles (L-NVs) have emerged as a promising solution to these challenges, offering enhanced stability, targeted delivery, and improved therapeutic efficacy. However, the transition of L-NVs from laboratory research to commercial application is fraught with regulatory hurdles, manufacturing complexities, and the need for rigorous safety and efficacy assessments. This chapter introduces the extensive range of L-NVs currently available, focusing on the latest generation of non-liposomal L-NVs, and highlighting their similarities and differences.

 

Author(s) Details

Shibangi Mukhopadhyay
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Nidhi Agrawal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Meenakshi Jaiswal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

S.K. Lanjhiyana
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Alpana Ram
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Rashmi Dewangan
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Rajkumar Sironiya
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh, 495009, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/prrat/v5/1816

Study on the Effect of β-Cyclodextrin on Phospholipids and Cholesterol of the Milk Fat Globule Membrane | Chapter 12 | Emerging Challenges in Agriculture and Food Science Vol. 4

 Phospholipids, like cholesterol, are found on the milk globule membrane (MFGM). The goal of this study was to see how -cyclodextrin (β-CD) affected phospholipids and cholesterol in raw pasteurised milk, in order to remove cholesterol from the milk fat. Total phospholipids in β-CD treated milk reduced marginally, but the effect of the β-CD was not significant. β-CD is a highly effective oligosaccharide for eliminating cholesterol from milk, with a reduction of more than 97%, and has no effect on individual phospholipids in the milk fat globule membrane (phosphatidylcholine, phosphatidylethanolamine, sphingomyelin, phosphatidylinositol, and phosphatidylserina).

Author(S) Details

Leocadio Alonso
Instituto de Productos Lácteos de Asturias (CSIC), 33300 Asturias, Spain and Food Agricultural Products Center and Department of Animal Science, Oklahoma State University, Stillwater 74075. Oklahoma, USA.

Paloma Cuesta
Food Agricultural Products Center and Department of Animal Science, Oklahoma State University, Stillwater 74075. Oklahoma, USA.

María V. Calvo
Instituto de Investigación en Ciencias de la Alimentación (CSIC-UAM), 28049 Madrid, Spain.

Javier Fontecha
Instituto de Investigación en Ciencias de la Alimentación (CSIC-UAM), 28049 Madrid, Spain.


View Book:- https://stm.bookpi.org/ECAFS-V4/article/view/6411