This chapter discusses the preparation and characterization
of poly (2-hydroxyethyl methacrylate) (PHEMA) nanoparticles for potential use
in controlled drug delivery. PHEMA nanoparticles were prepared using a modified
suspension polymerization technique. This study describes the preparation,
identification, and structural and morphological characterization of PHEMA
nanoparticles. PHEMA nanoparticles have been characterized using Fourier
Transform Infrared Spectroscopy (FTIR), scanning electron microscopy (SEM), and
particle size analysis. FTIR is used to confirm the presence of specific
functional groups within the PHEMA structure, while particle size distribution
provides information about the dimensions and uniformity of the nanoparticles.
It is found that the nanoparticles have having size of up to 100 nm and are
almost identical in shape. The small size of nanoparticles makes them a
suitable candidate for biomedical and pharmaceutical applications, especially
in the controlled drug delivery field. PHEMA nanoparticles can encapsulate and
release drugs, making them effective for targeted drug delivery, such as in
cancer therapy. PHEMA nanoparticles are significant in biomedical applications
due to their biocompatibility, tenable properties, and ability to serve as
drug-delivery vehicles. Their high water content, low toxicity, and tissue
compatibility make them suitable for a variety of medical devices and
therapies, including soft contact lenses, drug delivery systems, and tissue
regeneration scaffolds.
Author (s) Details
Huda Begam
Samrat Ashok Technological Institute, Vidisha (M.P), India.
A.K. Bajpa
Bose Memorial Research Laboratory, Department of Chemistry, Government
Autonomous Science College, Jabalpur (MP)-482001, India.
Please see the book here:- https://doi.org/10.9734/bpi/cmsrf/v3/5316
No comments:
Post a Comment