Traditionally
many of the medicinal plants are used by Assamese people to treat various
ailments, of them Dendrocnide sinuata and Chenopodium ambrosioides are used for
treating inflammation- related diseases. The present study was carried out to
investigate and verify the anti-inflammatory property of Dendrocnide sinuata
and Chenopodium ambrosioides by in-vitro human red blood cell (HRBC) membrane
stabilization method. In addition, the phytochemicals present in both the
plants were also analyzed. The results revealed that both the plant extracts
have HRBC membrane stabilizing activity with Chenopodium ambrosioides showing
greater efficacy than Dendrocnide sinuata and standard drug diclofenac.
However, the efficacy of the extracts was dose-dependent and was highest at
5,000 µg/ml. The analysis of the phytochemical analysis revealed the presence
of antiinflammatory compounds such as flavonoids and triterpenes in both the
plant samples. The study provides the evidence for anti-inflammatory efficacy
of both the plants.
Author(s) Details
Dr. Bisu Singh
Department of Zoology, School of Life Sciences, Sikkim University, Gangtok, Sikkim, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/192
Author(s) Details
Dr. Bisu Singh
Department of Zoology, School of Life Sciences, Sikkim University, Gangtok, Sikkim, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/192
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