Diaplant-Neo: Complex Therapy of Acute Intestinal Infections | Chapter 16 | Trends in Pharmaceutical Research and Development Vol.2

Aims: To develop the composition and technology of the combined capsules "Diaplant-Neo" for the complex treatment of gastrointestinal infections, investigation its antiexudative and spasmolytic activities. Objects of the Study: Nifuroxazide, Plantaglucidum, Calendula extract, encapsulation mass and Diaplant-Neocapsules. Subject of Study: Development of the composition and technology of the combined drug in the form of capsules for the treatment of gastrointestinal infections. Methods of the Study: Model of acute aseptic carrageenan inflammation, J. Setnicar method. Results: Technological scheme of the Diaplant-Neo production was developed. As a result of a study of Diaplant-Neo, it was found that antiexudative activity is not significantly inferior to the effect of sodium diclofenac, antispasmodic activity corresponds to the action of plantaglucid. Conclusion: The Diaplant-Neocapsuleshas broad pharmacological properties, comprehensively affects acute intestinal infections pharmacotherapy, reduces the phenomenon of polypharmacy.

Author(s) Details

L. O. Bobrytska
National University of Pharmacy, Kharkiv, Ukraine

V. V. Kovalev
National University of Pharmacy, Kharkiv, Ukraine

S. V. Spyrydonov 
National University of Pharmacy, Kharkiv, Ukraine.

T. I. Ivko
National Pirogov Memorial Medical University, Vinnytsya, Ukraine.

T. A. Germanyuk
National Pirogov Memorial Medical University, Vinnytsya, Ukraine.

N. A. Gordzievska
National Pirogov Memorial Medical University, Vinnytsya, Ukraine

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