Phytochemicals have always been a great matter of scientific
investigation because of enormous potential they possess in curing the problems
of mankind. Mother Nature is full of plants which have mixtures of
phytoconstituents in to each part of them. Such chemicals are obtained by
extraction techniques and other processes. However, their purity is the matter
of concern. So, scientific world is always in search of such techniques which
help in quantitative and qualitative evaluation of the phytoconstituents. Over
the years, many analytical techniques have come to the forefront with their
specific advantages and limitations. One such thrust area in the field of analytical
techniques is chromatography, comprising of simplest one like paper
chromatography, thin layer chromatography, gas chromatography to the complex
one like high performance liquid chromatography and hyphenated techniques like
Liquid Chromatography/Mass Spectroscopy (LC/MS) and Gas chromatography/ Mass
spectroscopy (GC / MS). The hyphenated techniques combine the specificity of
detection of mass spectroscopy with the resolving power of the liquid and gas
chromatography. This technique helps in proper separation of different
components. GC-MS technique makes the distinction of structurally similar
compounds easier with greater amount of precision with the help of mass
spectrometric analysis. The field has its application in separation and
purification of the phytoconstituents present in different plant extracts. It
is regarded as quantitative measurement method thereby helping in
identification of particular class of the phyto-components. Application of
LC-MS and GC-MS techniques has helped us to properly characterize such active
plant constituents. The chapters elucidated in this book by different authors
could help the students and researcher to provide a short review of the
techniques stated with plant based examples of different families and different
extracts. The team directs each enthusiastic researchers to go in depth to the
literature in order to have clear cut understanding of this contemporary area
of research.
Author (s) Details Gaurav M. Doshi
Department of Pharmacology, SVKM'S Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, Vile Parle (W), Mumbai-400056, India.
Atul P. Sherje
Department of Quality Assurance, SVKM’S Dr. Bhanuben Nanavati College of Pharmacy affiliated to University of Mumbai, Mithibai Campus, Vile Parle (W), Mumbai-400056, India.
Rakesh R. Somani
Dr. D Y Patil Deemed to be University, School of Pharmacy, Sector 7, Nerul, Navi Mumbai, India.
View Book :- http://bp.bookpi.org/index.php/bpi/catalog/book/197
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