Relationship between Body Mass Index and Biochemical Parameters in Subjects with and without Type 2 Diabetes Mellitus | Chapter 7 | Emerging Research in Medical Sciences Vol. 4

Type 2 diabetes mellitus is a chronic degenerative disease that belongs to the group of metabolic diseases, which is characterized by the presence of hyperglycemia, due to a failure in insulin secretion. Internationally, this condition represents a serious public health problem, since there are comorbidities that are also public health problems that favor the appearance of this health condition. Type 2 diabetes mellitus, being a metabolic disease, modifies a series of biomarkers or also called biochemical parameters that are determinants to achieve a diagnosis and follow-up of people who have this disease, for example: Fasting glucose, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides and glycosylated hemoglobin (HbA1c); the increase of these parameters in blood indicates the alteration of the different metabolic pathways and normal physiology of the organism due to the increase in hyperglycemia and insulin resistance. Other parameters that are also of important consideration are the presence of arterial hypertension which is a pressure equal to or greater than 140 mmHg of systolic pressure and a pressure equal to or greater than 90 mmHg; Another easy-touse tool is the body mass index (BMI), which helps to quickly classify the degree of obesity of a patient with normal weight, overweight or obesity. There are multiple causalities that favor the appearance of this health condition, some risk factors are smoking, overweight or obesity, physical inactivity, glycosylated hemoglobin (HbA1c), hypertension, dyslipidemias and unhealthy lifestyles.

Author (s) Details
Oscar Vega-Jiménez
School of Medicine, University of Celaya, Celaya, México.

Walter Herrera-Santoyo
School of Medicine, University of Celaya, Celaya, México

Luis Antonio Díaz-Becerril
School of Medicine, University of Celaya, Celaya, México.

Mayra del Carmen Jiménez Ortega
Division of Health Sciences and Engineering, Department of Nursing and Obstetrics, Campus Celaya-Salvatierra, University of Guanajuato, Celaya, México.

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